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Belinostat analytical pure 0.996

Belinostat is a pan-HDAC inhibitor with IC50 of 27 nM, with activity demonstrated in cisplatin-resistant tumors.

Belinostat analytical pure 0.999

Belinostat is a HDAC inhibitor with IC50 of 27 nM in a cell-free assay, with activity demonstrated in cisplatin-resistant tumors.

Betamethasone Sodium Phosphate

Betamethasone Sodium Phosphate is an organic sodium salt that is the disodium salt of betamethasone phosphate. It is an organic sodium salt and a tertiary alpha-hydroxy ketone.Betamethasone sodium phosphate binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression.

Copanlisib analytical pure 0.999

Copanlisib is a potent and highly selective reversible PI3K inhibitor for PI3Kα/β with IC50 of 0.469 nM/3.72 nM.

Crizotinib analytical pure 0.999

Crizotinib is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM, respectivley.

Cytarabine analytical pure 0.999

Cytarabine is an antimetabolic agent and DNA synthesis inhibitor with IC50 of 16 nM in wild-type CCRF-CEM cells.

Defactinib analytical pure 0.999

Defactinib is a potent FAK phosphorylation inhibitor and overcomes YB-1–mediated paclitaxel resistance by an AKT-dependent pathway.

Entinostat analytical pure 0.996

Entinostat strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM.

Everolimus analytical pure 0.986

Everolimus is a mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM.

Fevipiprant analytical pure 0.99

Fevipiprant is a selective, potent, reversible competitive CRTh2 antagonist with an in vitro dissociation constant KD value of 1.1nM at the CRTh2 receptor and an IC50 value of 0.44 nM for inhibition of PGD2-induced eosinophil shape change in human whole blood.

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