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Linaclotide LAB GRADE 97%

Linaclotide is an peptide agonist of guanylate cyclase 2C that is undergoing clinical trials for use in treating abdominal pain in patients with irritable bowel syndrome (IBS) accompanied by constipation. The drug also has promising outlooks for the treatment of gastroparesis, ulcerative colitis, chronic intestinal pseudo-obstruction (CIPO), and inertia coli as well. http://www.bocsci.com/linaclotide-cas-851199-59-2-item-84-152760.html

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Lithium Iodide Trihydrate

Lithium Iodide Trihydrate is used in pharmaceutical industry, photographic industry and intraocular lens synthesis.

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Medium Chain Triglyceride

Medium-chain triglycerides (MCTs) are medium-chain fatty acid esters of glycerol.

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Mepivacaine Hydrochloride

Mepivacaine hydrochloride is related chemically and pharmacologically to the amide-type local anesthetics. It contains an amide linkage between the aromatic nucleus and the amino group.

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Methylamine Hydrochloride

Methylamine hydrochloride is a White crystalline,free-flowing powder soluble in water widely used in Pharmaceutical applications, Soldering-flux and organic synthesis reactions.it also has wide application in Chemical synthesis, buffering agent. The dea lists methylamine as a precursor for many illicit drugs.

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Nicardipine hydrochloride

Nicardipine hydrochloride is a medication used to treat high blood pressure and angina. It belongs to the class of calcium channel blockers. Nicardipine inhibits the transmembrane influx of calcium ions into cardiac muscle and smooth muscle without changing serum calcium concentrations.

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Para Nitro Benzyl Bromide

Para Nitro Benzyl Bromide used as organic synthesis intermediate role in the pharmaceutical industry for the synthesis of sarcoma - formyl dissolved drugs.

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Para Nitro Chloro Benzene

Para Nitro Chloro Benzene is the organic pale yellow solid compound. It is a common intermediate in the production dyes, pigments, Paracetamol / Phenacetin pharma, pesticides and rubber chemicals. Para Nitro Chloro Benzene is prepared industrially by nitration of chlorobenzene.

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Peficitinib LAB GRADE 97%

Peficitinib, also known as ASP015K and JNJ-54781532, is a novel potent JAK inhibitor, which demonstrated potent efficacy in adjuvant-induced arthritis model in rats. ASP015K inhibited JAK1, JAK2, JAK3 and TYK2 enzyme activities with IC50 values of 3.9, 5.0, 0.71 and 4.8 nM, respectively. ASP015K inhibited the IL-2-induced proliferation of human T cells with an IC50value of 18 nM. Moreover, ASP015K was 14-fold more potent against JAK1/3 than JAK2/2 on the basis of EPO-induced proliferation of human leukemia cells. ASP015K has the potential to demonstrate JAK1/3-mediated immunomodulatory effects without the occurrence of JAK2-mediated hematopoietic effects. ASP015K may have potential use in prevention of rejection in solid organ transplantation; treatment of psoriasis; treatment of rheumatoid arthritis.http://www.bocsci.com/peficitinib-cas-944118-01-8-item-84-462759.html

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