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Clofarabine analytical pure 0.999

Clofarabine inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.

Cobimetinib analytical pure 0.999

Cobimetinib is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, showing more than 100-fold selectively for MEK1 over MEK2 and showed no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases.

Dacomitinib analytical pure 0.994

Dacomitinib is a potent, orally available, irreversible tyrosine kinase HER 1 (EGFR), HER2 and HER4 inhibitor with IC50 of 6, 45.7 and 73.7 nM for EGFR, ERBB2 and ERBB4, respectively.

Entrectinib analytical pure 0.999

Entrectinib is an oral pan-Trk, ROS1, and ALK inhibitor, with IC50 of 1.7/0.1/0.1 nM, 0.2 nM, and 1.6 nM for Trk A/B/C, ROS1, and ALK, respectively.

Epacadostat analytical pure 0.998

Epacadostat is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM and displays high selectivity over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO).

Favipiravir analytical pure 0.999

Favipiravir is an anti-viral compound with activity against many RNA viruses and an RNA-directed RNA polymerase NS5B inhibitor.

Fludarabine analytical pure 0.999

Fludarabine, a DNA synthesis inhibitor, is a chemotherapy drug used in the treatment of hematological malignancies.

Gemcitabine analytical pure 0.999

Gemcitabine is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.

Lipofermata analytical pure 0.999

Lipofermata is an inhibitor of fatty acid transport (FATP) with IC50 of 4.84 μM in Caco-2 cells.

NVP-TAE 684 analytical pure 0.992

NVP-TAE684 is a potent and selective ALK inhibitor with IC50 of 3 nM in a cell-free assay, 100-fold more sensitive for ALK than InsR.

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