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Cobimetinib analytical pure 0.999

Cobimetinib is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, showing more than 100-fold selectively for MEK1 over MEK2 and showed no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases.

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Dacomitinib analytical pure 0.994

Dacomitinib is a potent, orally available, irreversible tyrosine kinase HER 1 (EGFR), HER2 and HER4 inhibitor with IC50 of 6, 45.7 and 73.7 nM for EGFR, ERBB2 and ERBB4, respectively.

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Entrectinib analytical pure 0.999

Entrectinib is an oral pan-Trk, ROS1, and ALK inhibitor, with IC50 of 1.7/0.1/0.1 nM, 0.2 nM, and 1.6 nM for Trk A/B/C, ROS1, and ALK, respectively.

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Epacadostat analytical pure 0.998

Epacadostat is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM and displays high selectivity over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO).

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Favipiravir analytical pure 0.999

Favipiravir is an anti-viral compound with activity against many RNA viruses and an RNA-directed RNA polymerase NS5B inhibitor.

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Fludarabine analytical pure 0.999

Fludarabine, a DNA synthesis inhibitor, is a chemotherapy drug used in the treatment of hematological malignancies.

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Gemcitabine analytical pure 0.999

Gemcitabine is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.

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Lipofermata analytical pure 0.999

Lipofermata is an inhibitor of fatty acid transport (FATP) with IC50 of 4.84 μM in Caco-2 cells.

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NVP-TAE 684 analytical pure 0.992

NVP-TAE684 is a potent and selective ALK inhibitor with IC50 of 3 nM in a cell-free assay, 100-fold more sensitive for ALK than InsR.

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Napabucasin analytical pure 0.995

Napabucasin is a first-in-class cancer stemness inhibitor that targets STAT3.

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