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Ulixertinib analytical pure 0.999

Ulixertinib is a potent and reversible ERK1/ERK2 inhibitor with IC50 of < 0.3 nM for ERK2.

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Urolithin B analytical pure 0.998

Urolithin B is a natural product with anti-proliferative and antioxidant activity, which can penetrate the blood-brain barrier and may have neuroprotective effects against Alzheimer’s Disease.

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Vemurafenib analytical pure 0.999

Vemurafenib is a potent inhibitor of B-Raf V600E with IC50 of 31 nM in cell-free assay, and is 10-fold selective for B-Raf V600E over wild-type B-Raf in enzymatic assays while the cellular selectivity can exceed 100-fold.

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AZD1152-HQPA analytical pure 0.996

AZD1152-HQPA is the active metabolite of AZD-1152 and a highly selective Aurora B inhibitor with IC50 of 0.37 nM, ~100 fold selective for Aurora B over Aurora A.

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Cabozantinib analytical pure 0.999

Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.

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Diethyl(Tosyloxy)Methylphosphonate

Diethyl(Tosyloxy)Methylphosphonate as intermediate in the synthesis of nucleoside antiviral drugs.

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Elamipretide analytical pure 0.996

Elamipretide is a cardiolipin peroxidase inhibitor and mitochondria-targeting peptide, Improves Left Ventricular and Mitochondrial Function.

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Enzalutamide analytical pure 0.999

Enzalutamide is an androgen-receptor (AR) antagonist with IC50 of 36 nM in LNCaP cells.

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Geldanamycin analytical pure 0.994

Geldanamycin is a natural existing HSP90 inhibitor with Kd of 1.2 μM.

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JNJ-17203212 analytical pure 0.999

JNJ-17203212 is a selective TRPV1 antagonist, with IC50 of 65 nM and 102 nM for human TRPV1 and rat TRPV1.

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