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AZD1152-HQPA analytical pure 0.996

AZD1152-HQPA is the active metabolite of AZD-1152 and a highly selective Aurora B inhibitor with IC50 of 0.37 nM, ~100 fold selective for Aurora B over Aurora A.

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Cabozantinib analytical pure 0.999

Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.

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Diethyl(Tosyloxy)Methylphosphonate

Diethyl(Tosyloxy)Methylphosphonate as intermediate in the synthesis of nucleoside antiviral drugs.

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Elamipretide analytical pure 0.996

Elamipretide is a cardiolipin peroxidase inhibitor and mitochondria-targeting peptide, Improves Left Ventricular and Mitochondrial Function.

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Enzalutamide analytical pure 0.999

Enzalutamide is an androgen-receptor (AR) antagonist with IC50 of 36 nM in LNCaP cells.

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Geldanamycin analytical pure 0.994

Geldanamycin is a natural existing HSP90 inhibitor with Kd of 1.2 μM.

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JNJ-17203212 analytical pure 0.999

JNJ-17203212 is a selective TRPV1 antagonist, with IC50 of 65 nM and 102 nM for human TRPV1 and rat TRPV1.

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LY2409881 3HCl analytical pure 98%

LY2409881 3HCl is a selective inhibitor of IKK2 with IC50 of 30 nM and IC50 for IKK1 and other common kinases is at least one log higher.

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MK-2206 2HCl analytical pure 0.998

MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, respectively, showing no inhibitory activities against 250 other protein kinases observed.

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Panobinostat analytical pure 0.998

Panobinostat is a broad-spectrum HDAC inhibitor with IC50 of 5 nM in a cell-free assay.

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