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SCR7 Pyrazine analytical pure 0.995

SCR7 pyrazine is a specific DNA ligase IV inhibitor, which blocks nonhomologous end-joining (NHEJ).

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Staurosporine analytical pure 0.998

Staurosporine is a prototypical potent ATP-competitive multikinase inhibitor with IC50 of 0.7, 7, 8.5, 6, 20 nM for PKC, PKA,PKG, p60v-src tyrosine protein kinase, CaM kinase II, respectively.

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5-Fluorouracil analytical pure 0.999

5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools.

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Cytarabine HCl analytical pure 0.999

Cytarabine HCl is the hydrochloride form of Cytarabine. Cytarabine (Ara-C) is an antineoplastic and antileukemic agent in current clinical treatment.

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LDN-193189 HCl analytical pure 0.999

LDN-193189 HCl is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, exhibits 200-fold selectivity for BMP versus TGF-β.

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Pectolinarigenin analytical pure 98%

Pectolinarigenin is a dimethoxyflavone extracted from the leaves of Linaria vulgaris Mill and it has been found to specifically bind to the nuclear receptor RARγ (IC50 = 3.42 μM) to activate the JNK signaling pathway and induce apoptosis.

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Picropodophyllin analytical pure 98%

Picropodophyllotoxin is an orally active insulin-like growth factor-1 receptor (IGF-1R) inhibitor with IC50 of 1 nM, and exhibits little effect towards IR, FGFR, PDGFR and EGFR, and exerts no effects on microtubules and DNA topoisomerase II.

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Trichostatin A analytical pure 0.998

Trichostatin A is a selective and potent HDAC inhibitor with IC50 of ~1.8 nM and HDAC8 is the only known member of the HDAC-family that is not affected by TSA.

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Z-VAD(OMe)-FMK analytical pure 0.986

Z-VAD(OMe)-FMK is a cell-permeable, irreversible broad-spectrum caspase inhibitor, blocks all features of apoptosis.

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3-Methyladenine analytical pure 0.997

3-Methyladenine is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM.

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