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5-Fluorouracil analytical pure 0.999

5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools.

Cytarabine HCl analytical pure 0.999

Cytarabine HCl is the hydrochloride form of Cytarabine. Cytarabine (Ara-C) is an antineoplastic and antileukemic agent in current clinical treatment.

LDN-193189 HCl analytical pure 0.999

LDN-193189 HCl is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, exhibits 200-fold selectivity for BMP versus TGF-β.

Pectolinarigenin analytical pure 98%

Pectolinarigenin is a dimethoxyflavone extracted from the leaves of Linaria vulgaris Mill and it has been found to specifically bind to the nuclear receptor RARγ (IC50 = 3.42 μM) to activate the JNK signaling pathway and induce apoptosis.

Picropodophyllin analytical pure 98%

Picropodophyllotoxin is an orally active insulin-like growth factor-1 receptor (IGF-1R) inhibitor with IC50 of 1 nM, and exhibits little effect towards IR, FGFR, PDGFR and EGFR, and exerts no effects on microtubules and DNA topoisomerase II.

Trichostatin A analytical pure 0.998

Trichostatin A is a selective and potent HDAC inhibitor with IC50 of ~1.8 nM and HDAC8 is the only known member of the HDAC-family that is not affected by TSA.

Z-VAD(OMe)-FMK analytical pure 0.986

Z-VAD(OMe)-FMK is a cell-permeable, irreversible broad-spectrum caspase inhibitor, blocks all features of apoptosis.

3-Methyladenine analytical pure 0.997

3-Methyladenine is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM.

Cryptotanshinone analytical pure 0.99

Cryptotanshinone is a potent STAT3 inhibitor (IC50 =4.6 μM) and inhibits STAT3 Tyr705 phosphorylation in DU145 prostate cancer cells.

Gemcitabine HCl analytical pure 0.999

Gemcitabine HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.

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