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Cryptotanshinone analytical pure 0.99

Cryptotanshinone is a potent STAT3 inhibitor (IC50 =4.6 μM) and inhibits STAT3 Tyr705 phosphorylation in DU145 prostate cancer cells.

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Gemcitabine HCl analytical pure 0.999

Gemcitabine HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.

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MAT2A Inhibitor analytical pure 0.992

MAT2A inhibitor is a methionine adenosyltransferase 2A (MATA2) inhibitor.

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Palbociclib HCl analytical pure 0.982

Palbociclib HCl is a highly specific inhibitor of Cdk4 (IC50=11 nM) and Cdk6 (IC50=16 nM), having no activity against a panel of 36 additional protein kinases.

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Plerixafor 8HCl analytical pure 0.999

Plerixafor 8HCl is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.

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Quisinostat 2HCl analytical pure 0.99

Quisinostat 2HCl is a second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11, greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7.

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MK-4827 Tosylate analytical pure 0.994

MK-4827 tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM and with great activity in cancer cells with mutant BRCA-1 and BRCA-2 and > 330-fold selective against PARP3, V-PARP and Tank1.

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RGFP966 Racemate analytical pure 0.999

RGFP966 Racemate is the racemate form of HDAC3 inhibitor RGFP966.

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Sunitinib Malate analytical pure 0.998

Sunitinib Malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit.

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Imatinib Mesylate analytical pure 0.999

Imatinib Mesylate is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively.

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