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Z-VAD(OMe)-FMK analytical pure 0.986

Z-VAD(OMe)-FMK is a cell-permeable, irreversible broad-spectrum caspase inhibitor, blocks all features of apoptosis.

3-Methyladenine analytical pure 0.997

3-Methyladenine is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM.

Cryptotanshinone analytical pure 0.99

Cryptotanshinone is a potent STAT3 inhibitor (IC50 =4.6 μM) and inhibits STAT3 Tyr705 phosphorylation in DU145 prostate cancer cells.

Gemcitabine HCl analytical pure 0.999

Gemcitabine HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.

MAT2A Inhibitor analytical pure 0.992

MAT2A inhibitor is a methionine adenosyltransferase 2A (MATA2) inhibitor.

Palbociclib HCl analytical pure 0.982

Palbociclib HCl is a highly specific inhibitor of Cdk4 (IC50=11 nM) and Cdk6 (IC50=16 nM), having no activity against a panel of 36 additional protein kinases.

Plerixafor 8HCl analytical pure 0.999

Plerixafor 8HCl is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.

Quisinostat 2HCl analytical pure 0.99

Quisinostat 2HCl is a second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11, greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7.

MK-4827 Tosylate analytical pure 0.994

MK-4827 tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM and with great activity in cancer cells with mutant BRCA-1 and BRCA-2 and > 330-fold selective against PARP3, V-PARP and Tank1.

RGFP966 Racemate analytical pure 0.999

RGFP966 Racemate is the racemate form of HDAC3 inhibitor RGFP966.

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