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Ningetinib Tosylate analytical pure 0.994

Ningetinib tosylate is an inhibitor of tyrosine kinase inhibitor (TKI) and the IC50 for c-Met, VEGFR2 and Axl are 6.7 nM, 1.9 nM and <1.0 nM respectively.

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Rucaparib Phosphate analytical pure 0.996

Rucaparib phosphate is an inhibitor of PARP with Ki of 1.4 nM for PARP1, also showing binding affinity to eight other PARP domains.

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Tetrasodium Ethylene Diamine Tetraacetate

Tetrasodium Ethylene Diamine Tetraacetate is the salt resulting from the neutralization of ethylenediaminetetraacetic acid with four equivalents of sodium hydroxide. It is a chelating agent that sequesters a variety of polyvalent cations such as Calcium and Magnesium.

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Gemifloxacin Mesylate analytical pure 0.99

Gemifloxacin mesylate is an oral broad-spectrum quinolone antibacterial agent, used in the treatment of acute bacterial exacerbation of chronic bronchitis, and mild-to-moderate pneumonia.

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Lapatinib Ditosylate analytical pure 0.999

Lapatinib ditosylate is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively.

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PF-04929113 Mesylate analytical pure 0.997

PF-04929113 mesylate is a potent and selective Hsp90 inhibitor with an IC50 of median 50 nM.

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Gefitinib-Based PROTAC 3 analytical pure 0.99

Gefitinib-based PROTAC 3 is a VHL-recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11.7 nM and 22.3 nM for HCC827 cell (Exon 19 del) and H3255 cell (L858R).

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Palbociclib Isethionate analytical pure 0.999

Palbociclib isethionate is a highly specific inhibitor of Cdk4 (IC50=11 nM) and Cdk6 (IC50=16 nM), having no activity against a panel of 36 additional protein kinases.

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LY2835219 Methanesulfonate analytical pure 0.999

Abemaciclib Methanesulfonate is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM respectively, used for the treatment of advanced or metastatic breast cancers.

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Caffeic Acid Phenethyl Ester analytical pure 0.993

Caffeic acid phenethyl ester, a natural product isolated and purified from the barks of Cinnamomum cassia Presl, is a potent and specific inhibitor of NF-κB activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities.

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