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Ningetinib Tosylate analytical pure 0.994

Ningetinib tosylate is an inhibitor of tyrosine kinase inhibitor (TKI) and the IC50 for c-Met, VEGFR2 and Axl are 6.7 nM, 1.9 nM and <1.0 nM respectively.

Rucaparib Phosphate analytical pure 0.996

Rucaparib phosphate is an inhibitor of PARP with Ki of 1.4 nM for PARP1, also showing binding affinity to eight other PARP domains.

Tetrasodium Ethylene Diamine Tetraacetate

Tetrasodium Ethylene Diamine Tetraacetate is the salt resulting from the neutralization of ethylenediaminetetraacetic acid with four equivalents of sodium hydroxide. It is a chelating agent that sequesters a variety of polyvalent cations such as Calcium and Magnesium.

Gemifloxacin Mesylate analytical pure 0.99

Gemifloxacin mesylate is an oral broad-spectrum quinolone antibacterial agent, used in the treatment of acute bacterial exacerbation of chronic bronchitis, and mild-to-moderate pneumonia.

Lapatinib Ditosylate analytical pure 0.999

Lapatinib ditosylate is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively.

PF-04929113 Mesylate analytical pure 0.997

PF-04929113 mesylate is a potent and selective Hsp90 inhibitor with an IC50 of median 50 nM.

Gefitinib-Based PROTAC 3 analytical pure 0.99

Gefitinib-based PROTAC 3 is a VHL-recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11.7 nM and 22.3 nM for HCC827 cell (Exon 19 del) and H3255 cell (L858R).

Palbociclib Isethionate analytical pure 0.999

Palbociclib isethionate is a highly specific inhibitor of Cdk4 (IC50=11 nM) and Cdk6 (IC50=16 nM), having no activity against a panel of 36 additional protein kinases.

LY2835219 Methanesulfonate analytical pure 0.999

Abemaciclib Methanesulfonate is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM respectively, used for the treatment of advanced or metastatic breast cancers.

Caffeic Acid Phenethyl Ester analytical pure 0.993

Caffeic acid phenethyl ester, a natural product isolated and purified from the barks of Cinnamomum cassia Presl, is a potent and specific inhibitor of NF-κB activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities.

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