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Devapamil

Devapamil is a calcium channel blocker.

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Diazoxide

Diazoxide is a potassium channel activator, which causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. This switches off voltage-gated calcium ion channels which inhibits the generation of an action potential. It is used as a vasodilator in the treatment of acute hypertension or malignant hypertension. It is also used to decrease hypoglycemia due to the secretion of insulin in disease states such as insulinoma or congenital hyperinsulinism.

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Dicumarol

Dicumarol is an anticoagulant that functions as a Vitamin K antagonist. It is also used in biochemical experiments as an inhibitor of reductases. It is a natural chemical substance of combined plant and fungal origin. It is a derivative of coumarin, a bitter substance made by plants that does not itself affect coagulation, but which is transformed in mouldy feeds or silages by a number of species of fungi, into active dicumarol. Dicumarol does affect coagulation, and was discovered in mouldy wet sweet-clover hay, as the cause of a naturally-occurring bleeding disease in cattle. It was used along with heparin, for the treatment of deep venous thrombosis.

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Diltiazem

Diltiazem is a non-dihydropyridine member of the class of drugs known as calcium channel blockers, used in the treatment of hypertension, angina pectoris, and some types of arrhythmia. It is also an effective preventive medication for migraine. It is a class 3 anti-anginal drug, and a class IV antiarrhythmic. It is metabolized by and acts as an inhibitor of the CYP3A4 enzyme.

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Dimefline

Dimefline is a respiratory stimulant.

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Dithranol

Dithranol is an anthraquinone derivative.It accumulates in mitochondria where it interferes with the supply of energy to the cell, probably by the oxidation of dithranol releasing free radicals, and it impedes DNA replication and so slows the excessive cell division that occurs in psoriatic plaques.It is highly effective in the treatment of psoriasis.

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Docosanol

Docosanol is a saturated fatty alcohol used traditionally as an emollient, emulsifier, and thickener in cosmetics and as a nutritional supplement. It also approved as an antiviral agent for reducing the duration of cold sores caused by the herpes simplex virus. One of the most common side effects that has been reported from docosanol is headache. Headaches caused by the drug tend to be mild and can occur in any region of the head.

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Donepezil

Donepezil is a centrally acting reversible acetylcholinesterase inhibitor. Its main therapeutic use is in the palliative treatment of mild to moderate Alzheimer's disease. It has been tested in other cognitive disorders including Lewy body dementia and vascular dementia, but it is not currently approved for these indications. It has also been studied in patients with mild cognitive impairment, schizophrenia, attention deficit disorder, post-coronary bypass cognitive impairment, cognitive impairment associated with multiple sclerosis, CADASIL syndrome, and Down syndrome.

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Doxazosin

Doxazosin, a quinazoline compound is an alpha blocker used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia. It is an alpha-1 adrenergic receptor blocker that inhibits the binding of norepinephrine to the alpha-1 receptors on the membrane of vascular smooth muscle cells. The primary effect of this inhibition is relaxed vascular smooth muscle tone, which decreases peripheral vascular resistance, leading to decreased blood pressure.

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Econazole

Econazole nitrate is an antifungal medication of the imidazole class. It is used as a cream to treat skin infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch.

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