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Lapatinib Ditosylate analytical pure 0.999

Lapatinib ditosylate is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively.

PF-04929113 Mesylate analytical pure 0.997

PF-04929113 mesylate is a potent and selective Hsp90 inhibitor with an IC50 of median 50 nM.

Gefitinib-Based PROTAC 3 analytical pure 0.99

Gefitinib-based PROTAC 3 is a VHL-recruiting PROTAC that induces the degradation of EGFR and EGFR mutants with DC50 of 11.7 nM and 22.3 nM for HCC827 cell (Exon 19 del) and H3255 cell (L858R).

Palbociclib Isethionate analytical pure 0.999

Palbociclib isethionate is a highly specific inhibitor of Cdk4 (IC50=11 nM) and Cdk6 (IC50=16 nM), having no activity against a panel of 36 additional protein kinases.

LY2835219 Methanesulfonate analytical pure 0.999

Abemaciclib Methanesulfonate is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM respectively, used for the treatment of advanced or metastatic breast cancers.

Caffeic Acid Phenethyl Ester analytical pure 0.993

Caffeic acid phenethyl ester, a natural product isolated and purified from the barks of Cinnamomum cassia Presl, is a potent and specific inhibitor of NF-κB activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities.

Glucagon Receptor Antagonists-4 analytical pure 0.981

Glucagon receptor antagonists-4 is an selective antagonist of glucagon receptor.

Ammonium Pyrrolidine-1-Carbodithioate analytical pure 98%

Ammonium pyrrolidine-1-carbodithioate is a selective NF-κB inhibitor, inhibits translation of nitric oxide synthase mRNA to prevent induction.

Calcium Chloride

Calcium Chloride is comprised of calcium and chlorine elements. It is highly soluble, colorless crystalline inorganic salt, having the formula CaCl2. Calcium Chloride deduced from limestone as a by-product of the Solvay process. It is widely used for de-icing, to increase water hardness in swimming pools, food sequestrant, and also used in reinforced concrete.



IU1 is a reversible, small molecule inhibitor of deubiquitination by USP14 that demonstrates an IC50 value of 4-5 μM. IU1 selectively stimulates ubiquitin-dependent protein degradation in vitro at 34 μM and in MEF cells at 50 μM.

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