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WOP 40

WOP 40 is a pharmaceutical grade white mineral oil that consists out of a blend of processed base oils manufactured through hydrocracking saturated aliphatic and alicyclic nonpolar hydrocarbons. It is a colourless, transparent oily liquid,Free from fluorescence in daylight, Insoluble in water, slightly soluble, in alcohol and miscible with hydrocarbons. WOP 40 can be used in cosmetic creams, lotions, sustan oils,sunscreens, Pharmaceutical laxatives, topical ointments and in food packaging materials, food grade lubricants & grease.

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X-Gluc

X-Gluc, is a chromogenic substrate used in a variety of applications for the detection of the X-glucuronidase enzyme. Upon reduction, X-Gluc produces a localized colour, making it useful in identifying GUS gene presence in most cell types and for the detection of the GUS gene fusion marker in plants.

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ABT-737

ABT-737 is a potent small-molecule inhibitor of antiapoptotic proteins Bcl-2, Bcl-X(L) and Bcl-w with markedly higher affinity than previously reported compounds. ABT-737 induces apoptosis in MM cells, including those resistant to conventional therapy.

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AT-7867

AT7867 is a novel and potent inhibitor of both AKT and the downstream kinase p70 S6 kinase (p70S6K) and also of protein kinase A.

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ATL1102

ATL1102 is an antisense drug that ATL is developing for the treatment of multiple sclerosis, or MS. ATL1102 inhibits CD49d, a subunit of Very Late Antigen-4, or VLA-4. Studies in animal models have demonstrated that inhibiting VLA-4 positively affects a number of inflammatory diseases, including MS. We licensed ATL1102 to ATL in December 2001 and in February 2008, ATL licensed ATL1102 to Teva.

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ATL1103

ATL1103 is an antisense drug that targets the growth hormone receptor, or GHr, a receptor that, when inhibited, reduces the level of circulating insulin-like growth factor-1, or IGF-1, produced in the liver.

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AZD5438

AZD5438 is a potent inhibitor of cyclin-dependent kinase. AZD5438 showed significant antiproliferative activity in human tumor cell lines causing inhibition of the phosphorylation of cdk substrates pRb, nucleolin, protein phosphatase 1a, and RNA polymerase II COOH-terminal domain and blocking cell cycling at G(2)-M, S, and G(1) phases.

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Adjudin

Adjudin is a drug which is under development as a potential non-hormonal male contraceptive drug, which acts by blocking the production of sperm in the testes, but without affecting testosterone production.

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Aerosil

Aerosil is pure silicon dioxide, made from vaporized silicon tetrachloride oxidized in high-temperature flame with hydrogen and oxygen. Aggregated amorphous nano-sized primary particles gives free flow to powder materials. It gives thickening effect and thixotropy by dispersing to liquid materials. One of the most important applications of AEROSIL® fumed silica in the adhesives and sealants industry is its use as an active reinforcing filler to improve the mechanical properties of silicone sealants.

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Alpidem

Alpidem is an anxiolytic drug from the imidazopyridine family, related to the more well known sleeping medication zolpidem. Unlike zolpidem however, alpidem does not produce sedative effects at normal doses, and is instead used specifically for the treatment of anxiety. It was developed by Synthélabo. It was withdrawn from the French market by 1994 and is not approved for marketing anywhere in the world. It was known to act selectively on the α3 receptor subtype and to a lesser extent at the α1 subtype, of the benzodiazepine receptor. However the chemical structure of alpidem is not related to that of the benzodiazepines, and alpidem is thus sometimes referred to as a nonbenzodiazepine.

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