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LEXXEL is indicated for the treatment of hypertension. This fixed combination drug is not indicated for the initial therapy of hypertension. It is a fixed-dose combination of the ACE inhibitor enalapril maleate and the highly vascular selective calcium antagonist felodipine.
Niacin is an organic compound. It is a derivative of pyridine, with a carboxyl group at the 3-position. Niacin is a precursor to NAD+/NADH and NADP+/NADPH, which play essential metabolic roles in living cells. It is involved in both DNA repair, and the production of steroid hormones in the adrenal gland.
Oxygen is a member of the chalcogen group on the periodic table, and is a highly reactive nonmetallic period 2 element that readily forms compounds with almost all other elements. It was independently discovered by Carl Wilhelm Scheele, in Uppsala, in 1773 or earlier, and Joseph Priestley in Wiltshire, in 1774, but Priestley is often given priority because his work was published first. The name oxygen was coined in 1777 by Antoine Lavoisier, whose experiments with oxygen helped to discredit the popular phlogiston theory of combustion and corrosion. Uptake of oxygen from the air is the essential purpose of respiration, so oxygen supplementation is used in medicine. Treatment not only increases oxygen levels in the patient's blood, but has the secondary effect of decreasing resistance to blood flow in many types of diseased lungs, easing work load on the heart. Oxygen therapy is used to treat emphysema, pneumonia, some heart disorders, some disorders that cause increased pulmonary artery pressure, and any disease that impairs the body's ability to take up and use gaseous oxygen. Other uses of oxygen include the production of steel, plastics and textiles, rocket propellant, and life support in aircraft, submarines, spaceflight and diving.
RAF265 is a selective and potent inhibitor of B-Raf and VEGFR2 with IC50.
TAK-875 is a potent, selective, and orally bioavailable GPR40 agonist, with a pharmacokinetic profile enabling long-acting drug efficacy. TAK-875 showed potent plasma glucose-lowering action and insulinotropic action during an oral glucose tolerance test in female Wistar fatty rats with impaired glucose tolerance. TAK-875 is currently in clinical trials for the treatment of type 2 diabetes mellitus.
Unimax is a fixed-dose combination of the vascular selective calcium antagonist felodipine and the ACE inhibitor ramipril, for hypertension.
Uracil is a common and naturally occurring pyrimidine derivative.It is a planar, unsaturated compound that has the ability to absorb light.It was isolated by hydrolysis of yeast nuclein that was found in bovine thymus and spleen, herring sperm, and wheat germ.It is involved in the transmission of hereditary characteristics.Uracil is one of four nitrogenous bases found in the RNA molecule.It is the hydrogen bond acceptor and can form two hydrogen bonds.It can also bind with a ribose sugar to form the ribonucleoside uridine.It can be used for drug delivery and as a pharmaceutical,used to determine microbial contamination of tomatoes.Its derivatives are more often used as antiphotosynthetic herbicides, destroying weeds in cotton, sugar beet, turnips, soya, peas, sunflower crops, vineyards, berry plantations, and orchards.
VX-702, one of a series of second-generation, is an orally active p38 MAP kinase inhibitors, for the potential treatment of inflammation, rheumatoid arthritis and cardiovascular diseases.
WOP 40 is a pharmaceutical grade white mineral oil that consists out of a blend of processed base oils manufactured through hydrocracking saturated aliphatic and alicyclic nonpolar hydrocarbons. It is a colourless, transparent oily liquid,Free from fluorescence in daylight, Insoluble in water, slightly soluble, in alcohol and miscible with hydrocarbons. WOP 40 can be used in cosmetic creams, lotions, sustan oils,sunscreens, Pharmaceutical laxatives, topical ointments and in food packaging materials, food grade lubricants & grease.
X-Gluc, is a chromogenic substrate used in a variety of applications for the detection of the X-glucuronidase enzyme. Upon reduction, X-Gluc produces a localized colour, making it useful in identifying GUS gene presence in most cell types and for the detection of the GUS gene fusion marker in plants.
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