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Amrinone

Amrinone is a pyridine phosphodiesterase 3 inhibitor. It is a drug that may improve the prognosis in patients with congestive heart failure. Amrinone has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR). It is used in the treatment of congestive heart failure. It has been studied for use before coronary artery bypass surgery. it increases cardiac contractility, vasodilator, and it acts by inhibiting the breakdown of both cAMP and cGMP by the phosphodiesterase (PDE3) enzyme.

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Anethole

Anethole is an aromatic compound that occurs widely in nature, in essential oils. It contributes a large component of the distinctive flavors of anise and fennel, anise myrtle, liquorice and star anise. It has numerous commercial uses in multiple industries, and high potential for additional uses. Anethole is a flavoring substance of commercial value. In addition, it is distinctly sweet, measuring 13 times sweeter than sugar. It is perceived as being pleasant to the taste even at higher concentrations. It is unrelated to glycyrrhizic acid, which often co-occurs with it and also is very sweet. Anethole is used in alcoholic drinks, seasoning and confectionery applications, oral hygiene products, and in small quantities in natural berry flavors. Pharmaceutical drugs derived from or related to anethole include anisyldithiolthione, anethole dithione (ADT) and anethole trithione (ATT).

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Anipamil

Anipamil is a calcium channel blocker.

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Antimony

Antimony is a toxic chemical element. It is found in nature mainly as the sulfide mineral stibnite. Although the use of antimony is limited by its toxicity, its compounds have been of fundamental value in chemistry. Antimony compounds are prominent fire retardants found in many commercial and domestic products. Certain alloys are valuable for use in solders and ball bearings. An emerging application is the use of antimony in microelectronics. Few biological or medical applications exist for antimony. Treatments principally containing antimony are known as antimonials and are used as emetics. Antimony compounds are used as antiprotozoan drugs.

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Apocynin

Apocynin is a natural organic compound structurally related to vanillin. It has been isolated from a variety of plant sources and is being studied for its variety of pharmacological properties. It is used as an inhibitor of NADPH oxidase.

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Astatine

Astatine is the rarest naturally occurring element. It is produced by radioactive decay in nature, but due to its short half life it is found only in minute amounts. It was first produced by Dale R. Corson, Kenneth Ross MacKenzie, and Emilio Segrè in 1940. Some astatine isotopes have been used as alpha-particle emitters in science, and medical applications for astatine-211 have been tested.

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Atropine

Atropine is a naturally occurring tropane alkaloid extracted from deadly nightshade Jimson weed, mandrake and other plants of the family Solanaceae. Atropine is a racemic mixture of d-hyoscyamine and l-hyoscyamine. It is a secondary metabolite of these plants and serves as a drug with a wide variety of effects. It is a competitive antagonist for the muscarinic acetylcholine receptor types M1, M2, M3, M4 and M5. It is classified as an anticholinergic drug. Atropine increases firing of the sinoatrial node (SA) and conduction through the atrioventricular node (AV) of the heart, opposes the actions of the vagus nerve, blocks acetylcholine receptor sites, and decreases bronchial secretions. Atropine is also useful in treating second-degree heart block Mobitz Type 1, and also third-degree heart block with a high Purkinje or AV-nodal escape rhythm. It is usually not effective in second-degree heart block Mobitz type 2. Atropine is rapidly and well absorbed after intramuscular administration. Atropine disappears rapidly from the blood and is distributed throughout the various body tissues and fluids.

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Avanafil

Avanafil is a PDE5 inhibitor being developed for erectile dysfunction. It acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina.

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Azapride

Azapride is the azide derivative of the dopamine antagonist clebopride. It is an irreversible dopamine antagonist.

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Beatrice

Beatrice is a lesser-known psychedelic drug. It is an analog of Methamphetamine and a homolog of DOM. It was first synthesized by Alexander Shulgin. It produces a vague feeling of openness and receptiveness, and causes a stimulative effect. It also causes diarrhea.

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