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Anipamil

Anipamil is a calcium channel blocker.

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Antimony

Antimony is a toxic chemical element. It is found in nature mainly as the sulfide mineral stibnite. Although the use of antimony is limited by its toxicity, its compounds have been of fundamental value in chemistry. Antimony compounds are prominent fire retardants found in many commercial and domestic products. Certain alloys are valuable for use in solders and ball bearings. An emerging application is the use of antimony in microelectronics. Few biological or medical applications exist for antimony. Treatments principally containing antimony are known as antimonials and are used as emetics. Antimony compounds are used as antiprotozoan drugs.

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Apocynin

Apocynin is a natural organic compound structurally related to vanillin. It has been isolated from a variety of plant sources and is being studied for its variety of pharmacological properties. It is used as an inhibitor of NADPH oxidase.

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Astatine

Astatine is the rarest naturally occurring element. It is produced by radioactive decay in nature, but due to its short half life it is found only in minute amounts. It was first produced by Dale R. Corson, Kenneth Ross MacKenzie, and Emilio Segrè in 1940. Some astatine isotopes have been used as alpha-particle emitters in science, and medical applications for astatine-211 have been tested.

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Atropine

Atropine is a naturally occurring tropane alkaloid extracted from deadly nightshade Jimson weed, mandrake and other plants of the family Solanaceae. Atropine is a racemic mixture of d-hyoscyamine and l-hyoscyamine. It is a secondary metabolite of these plants and serves as a drug with a wide variety of effects. It is a competitive antagonist for the muscarinic acetylcholine receptor types M1, M2, M3, M4 and M5. It is classified as an anticholinergic drug. Atropine increases firing of the sinoatrial node (SA) and conduction through the atrioventricular node (AV) of the heart, opposes the actions of the vagus nerve, blocks acetylcholine receptor sites, and decreases bronchial secretions. Atropine is also useful in treating second-degree heart block Mobitz Type 1, and also third-degree heart block with a high Purkinje or AV-nodal escape rhythm. It is usually not effective in second-degree heart block Mobitz type 2. Atropine is rapidly and well absorbed after intramuscular administration. Atropine disappears rapidly from the blood and is distributed throughout the various body tissues and fluids.

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Avanafil

Avanafil is a PDE5 inhibitor being developed for erectile dysfunction. It acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina.

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Azapride

Azapride is the azide derivative of the dopamine antagonist clebopride. It is an irreversible dopamine antagonist.

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Beatrice

Beatrice is a lesser-known psychedelic drug. It is an analog of Methamphetamine and a homolog of DOM. It was first synthesized by Alexander Shulgin. It produces a vague feeling of openness and receptiveness, and causes a stimulative effect. It also causes diarrhea.

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Benmoxin

Benmoxin is an irreversible and nonselective monoamine oxidase inhibitor of the hydrazine class.It was synthesized in 1967 and was subsequently used as an antidepressant in Europe, but is now no longer marketed.

Properties
Bepridil

Bepridil is a calcium channel blocker that has well characterized anti-anginal properties and known but poorly characterized type 1 anti-arrhythmic and anti-hypertensive properties. It is not related chemically to other calcium channel blockers such as diltiazem hydrochloride, nifedipine and verapamil hydrochloride. Bepridil has inhibitory effects on both the slow calcium (L-type) and fast sodium inward currents in myocardial and vascular smooth muscle, interferes with calcium binding to calmodulin, and blocks both voltage and receptor operated calcium channels. Bepridil inhibits the transmembrane influx of calcium ions into cardiac and vascular smooth muscle. Bepridil regularly reduces heart rate and arterial pressure at rest and at a given level of exercise by dilating peripheral arterioles and reducing total peripheral resistance (afterload) against which the heart works.

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