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Aprobarbital

Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia. Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed. It works by binding to the GABAA receptor at either the alpha or the beta sub unit. These are binding sites that are distinct from GABA itself and also distinct from the benzodiazepine binding site.

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Aquayamycin

Aquayamycin is an anthraquinone. It is an inhibitor of the enzyme tyrosine hydroxylase.

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Arabinofuranosyluracil

Arabinofuranosyluracil is an antiviral agent. It is used for the treatment of severe acute respiratory syndrome (SARS).

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Arctiin

Arctiin is a lignan found in many plants of the Asteraceae family. It is the glucoside of arctigenin. Arctiin and arctigenin have shown anticancer effects.

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Arecoline

Arecoline is an alkaloid natural product found in the areca nut, the fruit of the areca palm. Owing to its muscarinic and nicotinic agonist properties, arecoline has shown improvement in the learning ability of healthy volunteers. Since one of the hallmarks of Alzheimer's disease is a cognitive decline, arecoline was suggested as a treatment to slow down this process and arecoline administered intravenously did indeed show modest verbal and spatial memory improvement in Alzheimer's patients, though due to arecoline's possible carcinogenic properties, it is not the first drug of choice for this degenerative disease. It has also been used medicinally as an antihelmintic.

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Arfendazam

Arfendazam is a drug which is a benzodiazepine derivative. It is a 1,5-benzodiazepine, with the nitrogen atoms located at positions 1 and 5 of the diazepine ring, and so is most closely related to other 1,5-benzodiazepines such as clobazam. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, but is a partial agonist at GABAA receptors, so the sedative effects are relatively mild and it produces muscle relaxant effects only at very high doses. It produces an active metabolite lofendazam, which is thought to be responsible for part of its effects.

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Arformoterol

Arformoterol is a long acting beta-adrenoceptor agonist drug indicated for the treatment of chronic obstructive pulmonary disease.

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Arginine Aspartate EP

Arginine Aspartate EP is used in the field of pharmaceutical and food additive.

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Aripiprazole

Aripiprazole is an atypical antipsychotic and antidepressant used in the treatment of schizophrenia, bipolar disorder, and clinical depression.

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Arnolol

Arnolol is a beta blocker.

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