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XMT-1107

XMT-1107 is a novel, first-in-class anti-angiogenic with broad potential across multiple oncology indications. XMT-1107 has demonstrated dramatically improved pharmacokinetics and no evidence of CNS toxicity, establishing it as a potential new anti-angiogenic drug with significant therapeutic advantages.

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Xanthine

Xanthine is a purine base found in most human body tissues and fluids and in other organisms. Xanthine is a product on the pathway of purine degradation. Xanthine is a purine base that’s an antecedent of uric acid and is generally found in muscle tissue, blood, urine and some plants. It is a water insoluble toxic yellowish white powder and acids that’s soluble in caustic soda. It is involved in purine degradation and is converted from hypoxanthine and converted to uric acid by xanthine oxidase. Xanthine derivatives are collectively known as xanthines, which are a group of alkaloids used as stimulants and bronchodilators.

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Xipamide

Xipamide is a sulfonamide diuretic drug. It is used for the treatment of oedema and hypertension.

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Yangonin

Yangonin is one of the six major kavalactones found in the kava plant. It displays marked in vitro toxicity on human hepatocytes with approximately 40% reduction in viability based on an ethidium bromide assay. The predominant mode of cell death turned out to be apoptosis rather than necrosis. No significant changes were observed in glutathione levels.

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Zinterol

Zinterol is a beta-adrenergic agonist.

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Zotepine

Zotepine is an atypical antipsychotic indicated for acute and chronic schizophrenia. It has been used in Germany since 1990 and Japan since 1982.

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m-Cresol

m-Cresol is a phenol. Amongst its uses it can be used as a solvent for dissolving polymers, most notably the conducting polymer polyaniline. When polyaniline is cast from a solution of m-cresol or a polyaniline film is exposed to m-cresol vapor the conductivity is higher than a polyaniline film cast without the presence of m-cresol.

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o,p'-DDD

Mitotane, or o,p'-DDD, is an antineoplastic medication used in the treatment of adrenocortical carcinoma. It is an isomer of DDD and is a derivative of DDT.[2] Its main use is in those patients who have persistent disease despite surgical resection, those who are not surgical candidates, or those who have metastatic disease. It has been produced by Bristol Myers Squibb SpA but it is marketed as an orphan drug due to the small number of patients in need of it. A 2007 study of 177 patients shows a significant increase in the recurrence-free interval after radical surgery followed by Mitotane when compared to surgery alone. Mitotane alters steroid peripheral metabolism, directly suppresses the adrenal cortex and alters cortisone metabolism leading to hypocortisolism. Side effects as reporte

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o-Cresol

o-Cresol is a phenol. It is an isomer of p-cresol, m-cresol and anisole. Cresols are used to dissolve other chemicals, as disinfectants and deodorizers, and to make specific chemicals that kill insect pests. They are found in many foods and in wood and tobacco smoke, crude oil, coal tar, and in brown mixtures such as creosote, cresolene and cresylic acids, which are wood preservatives.

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1-Butanol

Orchid Chemie make available to the customers 1-Butanol, a colourless chemical that is used extensively as a chemical intermediate and solvent. 1-Butanol has been processed using high grade ingredients and advanced techniques.1-Butanol serves many purposes in various paints, coatings, resins, dyes, textiles, degreasers sectors.

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