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Doxazosin, a quinazoline compound is an alpha blocker used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia. It is an alpha-1 adrenergic receptor blocker that inhibits the binding of norepinephrine to the alpha-1 receptors on the membrane of vascular smooth muscle cells. The primary effect of this inhibition is relaxed vascular smooth muscle tone, which decreases peripheral vascular resistance, leading to decreased blood pressure.

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Econazole nitrate is an antifungal medication of the imidazole class. It is used as a cream to treat skin infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch.

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Efavirenz is a non-nucleoside reverse transcriptase inhibitor and is used as part of highly active antiretroviral therapy for the treatment of a human immunodeficiency virus (HIV) type 1. It is also used in combination with other antiretroviral agents as part of an expanded postexposure prophylaxis regimen to reduce the risk of HIV infection in people exposed to a significant risk.

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Elfazepam is a drug which is a benzodiazepine derivative. Presumably it has sedative and anxiolytic actions like those of other benzodiazepines. It has appetite stimulating properties in animals. The mechanism for increasing feed intake is not clear and has been subject of investigation. It has been found that elfazepam suppresses gastric acid secretion.


Eliprodil is a drug which acts as an NMDA antagonist, binding to the polyamine modulatory site. It has neuroprotective and anticonvulsant effects in animal studies, but does not support self administration or substitute for phencyclidine, and does not produce sedation or amnesia. It was researched for the treatment of stroke and epilepsy but human trials failed to show clear beneficial effects.

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Enalapril is one of the angiotensin-converting enzyme inhibitors that is used to treat hypertension.Enalaprilat blocks the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in decreased plasma angiotensin II. As angiotensin II is a vasoconstrictor and a negative-feedback mediator for renin activity, lower concentrations result in a decrease in blood pressure and stimulation of baroreceptor reflex mechanisms, which leads to decreased vasopressor activity and to decreased aldosterone secretion. Enalaprilat may also act on kininase II, an enzyme identical to ACE that degrades the vasodilator bradykinin.

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Enflurane is a general inhalation anesthetic drug.It induces muscle relaxation and reduces pains sensitivity by altering tissue also decreases coronary vascular resistance and sensitizes the myocardium to circulating catecholamines,decrease in skeletal muscle tone.

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Enoximone is an imidazole phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.

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Ensaculin is a drug from the coumarin family, which has been researched as a potential treatment for dementia. It acts on a number of receptor systems, being both a weak NMDA antagonist and a 5HT1A agonist. Animal studies have shown promising nootropic effects, although efficacy in humans has yet to be proven. It was well tolerated in human trials, with the main side effect being orthostatic hypotension.


Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. Entecavir is a nucleoside analog that inhibits reverse transcription, DNA replication and transcription in the viral replication process.

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