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Masitinib

Masitinib is a tyrosine kinase.It can enhance the antiproliferative effects of gemcitabine (GEM) in human pancreatic cancer cells. It potently inhibited human and murine KIT with activating mutations in the juxtamembrane domain.

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Meclizine

Meclizine is an antihistamine considered to be an antiemetic. It is approved by the U.S. Food and Drug Administration to treat symptoms of motion sickness and for management of vertigo that stems from diseases affecting the vestibular system.

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Medazepam

Medazepam is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a long acting benzodiazepine drug.

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Mefenorex

Mefenorex is a stimulant drug which was used as an appetite suppressant. It is an amphetamine derivative which was developed in the 1970s and used for the treatment of obesity. It produces amphetamine as a metabolite, and has been withdrawn in many countries despite having only mild stimulant effects and relatively little abuse potential.

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Mefruside

Mefruside is a diuretic indicated for the treatment of edema and hypertension. It was developed by Bayer A.G.

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Meglumine

Meglumine is an amino sugar derived from sorbitol. It is often used as an excipient in pharmaceuticals and in conjunction with iodinated compounds incontrast media such as diatrizoate meglumine and iodipamide meglumine.

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Melatonin

Melatonin is a hormone found naturally in the body.It is made from an amino acid called tryptophan.It is implicated in the regulation of sleep, mood, and reproduction.

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Meldonium

Meldonium may be used to treat coronary artery disease. Meldonium has also been found to induce anticonvulsant and antihypnotic effects involving alpha 2-adrenergic receptors as well as nitric oxide-dependent mechanisms. This, in summary, shows that meldonium given in acute doses could be beneficial for the treatment of seizures and alcohol intoxication.Meldonium was added to the World Anti-Doping Agency (WADA) list of banned substances effective 1 January 2016 because of evidence of its use by athletes with the intention of enhancing performance.

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Melphalan

Melphalan is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents. An alkylating agent adds an alkyl group to DNA. It attaches the alkyl group to the guanine base of DNA, at the number 7 nitrogen atom of the imidazole ring. It is used to treat multiple myeloma and ovarian cancer, and occasionally malignant melanoma. The agent was first investigated as a possible drug for use in melanoma. It was not found to be effective, but has been found to be effective in the treatment of myeloma.

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Menadione

Menadione is a synthetic chemical compound sometimes used as a nutritional supplement because of its vitamin K activity. It is an analog of 1,4-naphthoquinone with a methyl group in the 2-position. It is used in the treatment of Hypoprothrombinemia. Large doses of menadione have been reported to cause adverse outcomes including hemolytic anemia due to G6PD deficiency, neonatal brain or liver damage, or neonatal death in some rare cases.

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