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13,14-Dihydro-15-Keto Prostaglandin D2

13,14-Dihydro-15-keto prostaglandin D2 ontains four deuterium atoms at the 3,3',4, and 4' positions.It is intended for use as an internal standard for the quantification of 13,14-dihydro-15-keto PGD2

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14-Ethoxymetopon

14-Ethoxymetopon is an opiate analogue that is a derivative of metopon which has been substituted with an ethoxy group at the 14-position. It is a highly potent analgesic drug several hundred times stronger than morphine.

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14-Methoxymetopon

14-Methoxymetopon is an opiate analogue that is a derivative of metopon which has been substituted with a methoxy group at the 14-position. It is a highly potent analgesic drug that is around 500x stronger than morphine when administered systemically; however, when given spinally or supraspinally, it exhibits analgesic activity up to a million fold greater than morphine. It binds strongly to the μ-opioid receptor and activates it to a greater extent than most similar opioid drugs. This produces an unusual pharmacological profile, and although 14-methoxymetopon acts as a potent μ-opioid full agonist in regards to some effects such as analgesia, a ceiling effect is seen on other effects such as constipation and respiratory depression.

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15-Deoxy-D-12,14-Prostaglandin J2

15-Deoxy-D-12,14-prostaglandin J2 is a naturally occurring endogenous ligand for peroxisome proliferator-activated receptor-γ.It induces synoviocyte apoptosis and suppresses adjuvant-induced arthritis in rats.

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17-Alpha-Hydroxy-Progesterone Caproate

17-Alpha-Hydroxy-Progesterone Caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). It is used for in pregnant women for the treatment of habitual and recurrent abortion, threatened abortion, and post-partum.

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18-Methylaminocoronaridine

18-Methylaminocoronaridine is a second generation synthetic derivative of ibogaine developed by the research team led by the pharmacologist Stanley D. Glick from the Albany Medical College and the chemist Martin E. Kuehne from the University of Vermont. In animal studies it has shown around twice the efficacy of the related compound 18-methoxycoronaridine (18-MC) at reducing self-administration of morphine when administered in an equivalent dose, although it is less effective than 18-MC at reducing methamphetamine administration. Similarly to 18-MC itself, 18-MAC acts primarily as a selective α3β4 nicotinic acetylcholine antagonist, and is even more selective than 18-MC with very little activity as an NMDA antagonist and only slight affinity for the delta opioid receptor.

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1H-1,2,3-Triazole-4-Thiol Sodium Salt

1H-1,2,3-Triazole-4-thiol Sodium Salt is used as intermediate of pharmaceutical cephalosporins.

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1H-Indazol-3-Amine

1H-Indazol-3-Amine has a wide application in the field of pharma as 3-aminoindazole could serve as an efficient hinge-binding template for kinase inhibitors.

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2 Cyano 4 Nitro Aniline

2 Cyano 4 Nitro Aniline is used as a solvent and chemical intermediate for the synthesis of pharmaceuticals, dyestuffs and rubber chemicals through the reactions of alkylation, condensation, esterification, hydrolysis, halogenation or nitration.

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