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Stavudine

Stavudine is a dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.Stavudine inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP and by its incorporation into viral DNA.Side effects include peripheral neuropathy tingling, burning, numbness, or pain in the hands or feet), fatal lactic acidosis has been reported in patients treated with stavudine (ZERIT) in combination with other antiretroviral agents, severe liver enlargement, inflammation (pain and swelling) of the liver, and liver failure.

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Streptose

Streptose is an unusual l-pentose.It is the component of streptomycin and streptobiosamine antibiotic drugs.

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Sucralose

Sucralose is a zero-calorie artificial sweetener. It is approximately 600 times as sweet as sucrose, twice as sweet as saccharin, and 3.3 times as sweet as aspartame. It is stable under heat and over a broad range of pH conditions. Therefore, it can be used in baking or in products that require a longer shelf life. The commercial success of sucralose-based products stems from its favorable comparison to other low-calorie sweeteners in terms of taste, stability, and safety. Sucralose is used as a replacement for, or in combination with, other artificial or natural sweeteners such as aspartame, acesulfame potassium or high-fructose corn syrup. It is used in products such as candy, breakfast bars and soft drinks. It is also used in canned fruits wherein water and sucralose take the place of much higher calorie corn syrup based additives. Sucralose is a highly heat-stable artificial sweetener, allowing it to be used in many recipes with little or no sugar. Sucralose is available in a granulated form that allows for same-volume substitution with sugar.

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Sulazepam

Sulazepam is a drug which is a benzodiazepine derivative. It is the thioamide derivative of diazepam. It is metabolised into diazepam, desmethyldiazepam and oxadiazepam. It has sedative, muscle relaxant, hypnotic, anticonvulsant and anxiolytic propertiess like those of other benzodiazepines.

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Sulpiride

Sulpiride is a atypical antipsychotic drug of the benzamide class used mainly in the treatment of psychosis associated with schizophrenia and major depressive disorder. It is more commonly used in Europe and Japan. Levosulpiride is its purified levo- isomer and is sold in India for similar purpose. So far it has not been approved in the United States and Canada. The drug has strong chemical and clinical similarities to the related antipsychotic amisulpride.

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Suriclone

Suriclone is a sedative and anxiolytic drug in the cyclopyrrolone family of drugs. It has a very similar pharmacological profile to the benzodiazepine family of drugs including sedative and anxiolytic properties but with less amnestic effects, and its chemical structure is quite different from that of the benzodiazepine drugs. The mechanism of action by which suriclone produces its sedative and anxiolytic effects is by modulating GABAA receptors, although suriclone is more subtype-selective than most benzodiazepines.

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Tadalafil

Tadalafil is a PDE5 inhibitor, currently marketed in pill form for treating erectile dysfunction (ED) for the treatment of pulmonary arterial hypertension. It initially was developed by the biotechnology company ICOS. The most common side effects when using tadalafil are headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. These side effects reflect the ability of PDE5 inhibition to vasodilate (cause blood vessels to widen) and usually go away after a few hours. Back pain and muscle aches can occur 12 to 24 hours after taking the drug, and the symptom usually disappears after 48 hours.

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Talnetant

Talnetant is a neurokinin 3 receptor antagonist developed by GlaxoSmithKline, which is being researched for several different functions, primarily for irritable bowel syndrome and as a potential antipsychotic drug for the treatment of schizophrenia.

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Tamoxifen

Tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, hence tamoxifen may be characterized as a mixed agonist/antagonist. It has been the standard endocrine therapy for hormone receptor-positive early breast cancer in pre-menopausal women, although aromatase inhibitors have been proposed.

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Taxifolin

Taxifolin is a flavanonol, a type of flavonoid. It can be found in the açaí palm, in the Siberian larch and in the silymarin extract from the milk thistle seeds. It is also found in small quantities in red onion. It acts as a potential chemopreventive agent by regulating genes via an ARE-dependent mechanism. It has shown to inhibit the ovarian cancer cell growth in a dose-dependent manner. The capacity of taxifolin to stimulate fibril formation and promote stabilization of fibrillar forms of collagen can be used in medicine. Also taxifolin inhibited the cellular melanogenesis as effectively as arbutin, one of the most widely used hypopigmenting agents in cosmetics.

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