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Tolgabide

Tolgabide is a drug which was patented by Synthélabo as an anticonvulsant but was never marketed. It is an analogue of progabide and acts similarly to it as a prodrug of GABA, and therefore as an indirect agonist of the GABA receptors.

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Tolrestat

Tolrestat is an aldose reductase inhibitor which was approved for the control of certain diabetic complications. Tolrestat binds to a site distinct from the chloride transport site and binds to one half of the transporters at 5 x 10(-7) mol/L in the absence of chloride and at 3.6 x 10(-5) mol/L in physiologic chloride concentrations.

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Tolvaptan

Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist used to treat hyponatremia associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone. It is also in fast-track clinical trials for polycystic kidney disease. In a 2004 trial, tolvaptan, when administered with traditional diuretics, was noted to increase excretion of excess fluids and improve blood sodium levels in patients with heart failure without producing side effects such as hypotension or hypokalemia and without having an adverse effect on kidney function.

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Trazodone

Trazodone is an antidepressant of the serotonin antagonist and reuptake inhibitor class. It is a phenylpiperazine compound. It also has anxiolytic, and hypnotic effects. It has considerably less prominent anticholinergic and sexual side effects than most of the tricyclic antidepressants.

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Tretinoin

Tretinoin also known as all-trans retinoic acid (ATRA), is medication used for the treatment of acne and acute promyelocytic leukemia.It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.Tretinoin is most commonly used to treat acne.It is also used off-label to treat and reduce the appearance of stretch marks by increasing collagen production in the dermis.Tretinoin is used to induce remission in people with acute promyelocytic leukemia who have a mutation (the t(15;17) translocation 160 and/or the presence of the PML/RARα gene) and who don't respond to anthracyclines or can't take that class of drug. It is not used for maintenance therapy.

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Triacetin

Triacetin is the triester of glycerol and acetic acid. It is an artificial chemical compound, commonly used as a food additive, for instance as a solvent in flavourings, and for its humectant function. It is also a component of casting liquor with TG and as an excipient in pharmaceutical products where it is used as a humectant, a plasticizer, and as a solvent. It can also be used as a fuel additive as an antiknock agent which can reduce engine knocking in gasoline, and to improve cold and viscosity properties of biodiesel.

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Triazolam

Triazolam is a benzodiazepine derivative drug. It possesses pharmacological properties similar to that of other benzodiazepines, but it is generally only used as a sedative to treat severe insomnia. In addition to the hypnotic properties, triazolam also possesses, amnesic, anxiolytic, sedative, anticonvulsant and muscle relaxant properties. Due to its short half-life, triazolam is not effective for patients that suffer from frequent awakenings or early wakening.

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Triclofos

Triclofos is a sedative drug used rarely for treating insomnia, usually as a second-line treatment after other drugs have failed. This drug should only be used for the short term relief of severe insomnia and should not be mixed with alcohol or other depressant drugs. Patients should not drive or use machinery after taking triclofos. It is a prodrug which is metabolised in the liver into the active drug trichloroethanol. This delayed action means that the half-life of triclofos is fairly long and it may cause drowsiness the next day.

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Tripamide

Tripamide is a new diuretic derived from a sulfonamide nucleus that has both antihypertensive and natriuretic properties.

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Uldazepam

Uldazepam is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those of other benzodiazepines.

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