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Tenoretic is for the treatment of hypertension. It combines the antihypertensive activity of two agents: a β1-selective (cardioselective) hydrophilic blocking agent (atenolol, Tenormin) and a monosulfonamyl diuretic (chlorthalidone).
Thiophene is the heterocyclic compound, consisting of a flat five-membered ring, it is aromatic as indicated by its extensive substitution reactions. Thiophenes are widely used as building blocks in many agrochemicals and pharmaceuticals. The benzene ring of a biologically active compound may often be replaced by a thiophene without loss of activity.
Thyme oil is extracted from leaves and flowering tops of Thymus vulgaris. The main component Thymol is a powerful antiseptic. Thymol has been reported for its antibacterial, antiviral, and anti-fungal action, kills the anthrax bacillus, the typhoid bacillus, meningococcus, and the agent responsible for tuberculosis and is active against salmonella and staphylococcus bacteria. It has also been studied for its effects on gingivitis and plaque-caused organisms in the mouth and is used in mouth washes (Listerine) for its antiseptic actions.
Tiopronin is a prescription thiol drug used to control the rate of cystine precipitation and excretion in the disease cystinuria.It may also be used for Wilson's disease and certain types of rare arthritis.
Tiqueside is a synthetic saponin developed to treat hypercholesterolemia by inhibiting the absorption of biliary and dietary cholesterol.It produces a dose-dependent reduction in plasma LDL cholesterol levels in the hypercholesterolemic patients and resulting in a reduction in serum LDL cholesterol levels.
Tirofiban is an antiplatelet drug. It belongs to a class of antiplatelet named glycoprotein IIb/IIIa inhibitors. It is the first drug candidate whose origins can be traced to a pharmacophore-based virtual screening lead.
Tivozanib is an oral VEGF receptor tyrosine kinase inhibitor. It is undergoing clinical trial investigation for the treatment of renal cell carcinomas.It is designed to inhibit all three VEGF receptors.
Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase. It is used in the treatment of Parkinson's disease as an adjunct to levodopa and carbidopa medication.
Tolgabide is a drug which was patented by Synthélabo as an anticonvulsant but was never marketed. It is an analogue of progabide and acts similarly to it as a prodrug of GABA, and therefore as an indirect agonist of the GABA receptors.
Tolrestat is an aldose reductase inhibitor which was approved for the control of certain diabetic complications. Tolrestat binds to a site distinct from the chloride transport site and binds to one half of the transporters at 5 x 10(-7) mol/L in the absence of chloride and at 3.6 x 10(-5) mol/L in physiologic chloride concentrations.
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