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Zacopride

Zacopride is a potent antagonist at the 5HT3 receptor and an agonist at the 5HT4 receptor. It has anxiolytic and nootropic effects in animal models, with the (R) enantiomer being the more active form. It also has antiemetic and pro-respiratory effects, both reducing sleep apnoea and reversing opioid-induced respiratory depression in animal studies.

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Zanamivir

Zanamivir is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus. It was the first neuraminidase inhibitor commercially developed. It has not been known to cause toxic effects, does not spread around through the body's systemic circulation and shows no signs of viral resistance from any flu.

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Zapizolam

Zapizolam is a pyridodiazepine drug, which is a benzodiazepine analog, specifically the pyridodiazepine analog of triazolam. Presumably it has sedative and anxiolytic effects similar to those produced by benzodiazepine derivatives.

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Zomepirac

Zomepirac is an orally effective nonsteroidal anti-inflammatory drug that has antipyretic actions. It was developed by McNeil Pharmaceutical and approved by the FDA in 1980. Due to its clinical effectiveness, it was preferred by doctors in many situations and obtained a large share of the analgesics market; however, it was subsequently withdrawn in March 1983 due to its tendency to cause serious anaphylaxis in an unpredictable subset of the patient population.

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