Skin care chemicals - suppliers, manufacturers, exporters

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Elevance Soft CG-100

Elevance Soft CG-100 a line of plant-based emollients, can be used in a wide range of personal care applications, including skin, hair and cosmetic products. Elevance Soft CG-100 is a 100 percent renewable, plant-based material. The compatibility and performance of it allow formulations to be free from PEG, paraben, petrolatum and silicone. It provides increased gloss in skin care applications and increased shine and frizz control for hair products.

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Gamma Poly-Glutamic Acid FOOD GRADE >90%

Gamma Poly-glutamic acid (γ-PGA) is a natural occurring, multi-functional, and

biodegradable biopolymer. It is produced through fermentation by Bacillus subtilis using glutamic acid. PGA is consists of glutamic acid monomers crosslinked between α-amino and γ-carboxyl groups, and the molecular weight of PGA is usually between 500~5,000 kDa. It is water-soluble, edible and non-toxictowards human, and is environment friendly. It has broad applications in the fields of medicine, food, cosmetics, and water treatment.

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Gamma Polyglutamic Acid Technical 90%

Gamma Poly-glutamic acid (γ-PGA) is a natural occurring, multi-functional, and biodegradable biopolymer. It is produced through fermentation by Bacillus subtilis using glutamic acid. PGA is consists of glutamic acid monomers crosslinked between α-amino and γ-carboxyl groups, and the molecular weight of PGA is usually between 500~5,000 kDa. It is water-soluble, edible and non-toxictowards human, and is environment friendly. It has broad applications in the fields of medicine, food, cosmetics, and water treatment.

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Heparin Sodium USP 95%

Heparin Sodium is the sodium salt of sulfated glycosaminoglycans and is present as a mixture of heterogeneous molecules varying in molecular weights that work against different factors of the blood clotting spectrum. It is obtained from porcine intestinal mucosa.Heparin Sodium is composed of polymers of alternating derivatives of α-D-glucosamido (N-sulfated, O-sulfated, or N-acetylated) and O-sulfated uronic acid (α-L-iduronic acid or β-D-glucuronic acid). The component activities of the mixture are in ratios corresponding to the USP specification. These components have the property of prolonging the clotting time of blood. This occurs mainly through the formation of a complexity of each component with the plasma proteins antithrombin and heparin cofactor II to potentiate the inactivation of thrombin (factor IIa). Other coagulation proteases in the clotting sequence, such as activated factor X (factor Xa), are also inhibited.

Application:
Heparin Sodium is a naturally-occurring anticoagulant used for anticoagulation for Cardiovascular Disease.Heparin Sodium Salt is widely used as an injectable anticoagulant. It can also be used to form an inner anticoagulant surface on various experimental and medical devices such as test tubes and renal dialysis machines.

Heparin sodium, is a kind of acid mucopolysaccharides compounds.is an anti clotting drug, on a number of links in coagulation process to intervene, prolonged clotting time and thrombin time. And the application range is not limited to in vivo, in vitro threw a good anticoagulant effect, by fibrin, inhibiting platelet aggregation.

Heparin Sodium also can be used in cosmetic industry. Heparin sodium can be used as a hair tonic, nourishing cream acne products, eye cream, cosmetics raw materials. It can be added to the nutritional cream, eye cream, acne products and hair agent and other cosmetics to increase skin vascular permeability, improve the role of local vascular circulation, promote the supply of skin nutrition and the excretion of metabolic waste,Health care and skin care.

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Hydrolyzed sodium hyaluronate Technical 98%

Name: OLIGO-HA

INCI Name: Hydrolyzed sodium hyaluronate

Molecular weight: 3kDa~ 10 kDa

Cas: 9067-32-7

Appearance: White to off-white powder

Recommended Dosage: 0.1% ~ 0.5%

Shelf life: 2 years

Package: 100g/ bottle or 1kg/bag

 

Hydrolyzed Sodium Hyaluronate is produced by enzymatic degradation thus resulting in higher purity, high anti-oxidant activity, high moisture retention, and high capacity for sun repair. The low molecular weight penetrates the skin and nourishes it deeply. It exhibits quick penetration with deep nourishment. It has high capacity for sun repair and has low hygroscopic potential in relatively high humidity. Imparts softness, supple feel and moisture to the skin.

 

Hydrolyzed sodium hyaluronate is an ultra-low molecular weight hyaluronic acid, designed for better skin penetration. With its characteristic advantage, Hydrolyzed sodium hyaluronate maximizes skin moisturizing and activates the function of stemness in the epidermis and promotes cell differentiation, preventing skin aging.

 

Hydrolyzed sodium hyaluronate can penetrate through skin deeply and rapidly, which will give new features to cosmetics, including raising HA content in the skin, deep hydrating, activating the skin, anti-aging, anti-oxidation, repairing skin damage, and deeply moisturizing, etc.

 

Hydrolyzed sodium hyaluronate can be applied in a series of products, such as eye cream, eye shadow, serum, moisturizing cream, sunblock cream, BB cream, lipstick, cleanser, toner, moisturizer, facial mask and scrub, emulsion, lotion, gel, foundation, blush, hydrating gels, bodycare products, haircare products.

 

Detailed functions of hydrolyzed sodium hyaluronate

1. Moisturizing

HA holds more water than any other molecule in the body and is necessary to keep collagen hydrated and youthful.

2. Lubrication and film formation

hydrolyzed sodium hyaluronate is a high molecular weight polymer with strong lubricating and filming. When it is smeared on the skin it can form a film and make the skin feel lubricating. Film formed on the surface of the hair can moisturize and lubricate the hair and eliminate static electricity. The hair becomes soft and easy to comb.

3. Injured-skin repairing and preventing

1) Accelerate the skin regeneration of injury by promoting proliferation and division of cuticle cells, and clear away oxygen free radical.

2) When formulated with EGF and Heparin, it can accelerate the regeneration of cuticle cells, keep skin delicate, smooth and elastic.

3) Prevent skin from being injured, relieve pain and accelerate wound healing of scald and burn. Low molecular weight sodium hyalurate is significant helpful for the healing of erythema and trauma on the skin.

4. Nutrition

Low molecular weight sodium hyalurate can reach the corium layer so as to improving the content of water,nourishing skin and expanding blood capillary, improving microcirculation and promoting absorption of nutriment. So the skin will be smooth, elastic and not easy to age.

 

Hydrolyzed sodium hyaluronate as a safe and effective cosmetic ingredient has many advantages as following:

1、Transdermal absorption: Hydrolyzed sodium hyaluronate can penetrate into the skin with an absorption rate that can reach 69.5%.

2、Repairing damaged cells:Hydrolyzed sodium hyaluronate can repair the skin cells damaged by ultraviolet irradiation, increase cellular activity and cellular proliferation.

3、Scavenging free radicals: Hydrolyzed sodium hyaluronate can effectively scavenge Reactive Oxygen Free Radicals (ROS) induced by ultraviolet irradiation, so it can slow down the skin aging process by good anti-oxidation capability.

4、Deep moisturizing: Hydrolyzed sodium hyaluronate can penetrate into the skin, hydrating the epidermis and dermis. HA with high molecular weight has also good moisturizing capability by forming a film on the surface of skin. When Hydrolyzed sodium hyaluronate and HA with high molecular weight are used in formulation together a remarkable synergistic effect is observed.

5、Anti-aging: Hydrolyzed sodium hyaluronate can significantly enhancing skin elasticity, strengthening the skin barrier, reducing skin wrinkles.

 

Remarks

1.Use pure water or distilled water to dissolve to guarantee the fine transparency.

2.Heating can accelerate the dissolution of HA.

3.Hydrolyzed sodium hyaluronate is a kind of biological polysaccharide. It is better to be used up once be dissolved. If there is much left, please store it with preservative to avoid microbial pollution.

4.Hydrolyzed sodium hyaluronate should not be used together with cationic emulgator or cationic preservative at the same time. Failure to do so may result in turbid or precipitate.

5.Hydrolyzed sodium hyaluronate is very hygroscopic, so it should be stored air tightly in a dry and low temperature (2℃-10 ℃) place.

6. Much better skincare efficacy can be obtained when combined with common HA.

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Kathon Methylisothiazolinone /Methylchloroisothiazolinone Technical 99%

It is a rapidly biodegradable, broad-spectrum preservative for rinse-off personal care products. It is used as hair care additives and skin care additives.This product is effective for the preservation of body washes, conditioners, liquid soaps, shampoos and wipes.
The active ingredients are two isothiazolinones, identified by the IUPAC system of nomenclature as: 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl- 4-isothiazolin-3-one.
It is totally miscible in water, lower alcohols and glycols and has low solubility in hydrocarbons.

Features and Benefits
Good compatibility with ionic,non-ionic surfactants and emulsifiers, water soluble additives, irrespective of their ionic nature
Maintain good bacteriostatic effect
Effective over the entire pH range normally encountered in cosmetics
No color or odor imparted to cosmetic products
Low toxicity at recommended use levels
Rapidly biodegradable
Non-persistent in the environment
Not bioaccumulating
Antibacterial effect against gram positive bacteria, gram negative bacteria, including pseudomonas.
It also has a certain inhibitory effect on fungi, which can inhibit the growth of microorganisms, and the minimum inhibitory concentration is 0.015~0.06%. (active ingredient 2.25~9ppm).

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Kojic Acid Dipalmitate

Kojic Acid Dipalmitate is a topical cream formulation indicated for the treatment of post-inflammatory hyperpigmentation, melasma and hyper-melanotic skin pigmentation disorders. Kojic Acid Dipalmitate can lighten the skin pigmentation and corrects discoloration in adults.

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L-carnosine Technical 99.0%

L-Carnosine

INCI name: Carnosine

CAS:305-84-0

EINECS/ELINCS No: 206-169-9

Molecular Formula: C9H14N4O3
Molecular Mass: 226.23

 

Specification:

Appearance: white or off-white powder

Specific Optical Rotation : +20.0°?+22.0°

Melting Point: 250?265?

pH( water solution): 7.5?8.5

Heavy Metal: ≤10ppm
Assay : 99.0%?101.0% (dried basis)
Related Substance: the single impurity ≤0.15%

Package and Storage Condition: 25kg/drum, store and seal away from light.
 

Application:

Skin conditioning

Scavenging free radicals, anti-oxidation, anti-aging .

 

Carnosine is a nature identical multi-functional anti-aging peptide. It stops the oxidative damage acting as an antioxidant agent, a ROS scavenger, metal ions chelating, and it stimulates Collagen synthesis.

Carnosine helps to prevent skin collagen cross-linking which leads to loss of elasticity and wrinkles. L-Carnosine is a Super antioxidant that quenches even the most destructive free radicals: The hydroxyl and the peroxyl radicals, superoxide, and singlet oxygen. Carnosine helps to chelate ionic metals(flush toxins from the body).

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Methylvinylether/Maleic Acid Copolymer Solution Technical appr.15%

These polymers are free acid form of the copolymer of Methylvinyl ether and Maleic Anhdride,in liquid form.Avalilable in a range of Molecular weights with tunable rheological properties.Those polymers soluble in water,serve as excellent film formers and bioadhesive/mucosal adhesives.

Specifications

YR-VM/MA20SL

YR-VM/MA80SL

YR-VM/MA100SL

YR-VM/MA200SL

Appearance

Slightly hazy viscous liquid

pH Value(5% in water)

1.5~2.5

1.5~2.5

1.5~2.5

1.5~2.5

Active Conent

12~15%

12~15%

12~15%

12~15%

Color(APHA)

200 max.

200 max.

200 max.

2000 max.

Specific Viscosity(1% in water)

0.2~1.0

1.0~2.5

2.5~2.4

4.0~10.0

Heavy Metals

7 ppm max.

7 ppm max.

7 ppm max.

7 ppm max.

Total Aerobic Plate Count

500cfu/g max.

500cfu/g max.

500cfu/g max.

500cfu/g max.

Mold/Yeast

500cfu/g max.

500cfu/g max.

500cfu/g max.

500cfu/g max.

Staphylococcus Aureus

Negative

Negative

Negative

Negative

Salmonella

Negative

Negative

Negative

Negative

Pseudomonas Aeruginosa

Negative

Negative

Negative

Negative

E.Coli

Negative

Negative

Negative

Negative

G-bacilli

Negative

Negative

Negative

Negative

 

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Methylvinylether/Maleic Anhydride Copolymer Technical 98% min.

Insoluble in water , soluble in THF , Acetone , etc.Hydrolysis happens in

water under proper condition.For production of di-acid products and half ester produrcts.

Specifications

YR-VM/MA AP1

YR-VM/MA AP2

YR-VM/MA AP3

YR-VM/MA AP4

Appearance:

Whiter to off-white free flowing powder

Specific Viscosity(1% in 2-Butanone):

0.1~0.5

0.5~1

1.0~1.5

1.5~2.5

2.5~4.0

Molecular Weight:

130,000~200,000

200,000~500,000

500,000~1,000,0000

1,000,000~1,800,000

1,800,000~2,000,000

Volatiles:

2.0% max.

Active Content:

98% min.

Residue Maleic Anhydride

Negative

 

 

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