2,2-Dihydroxy-1,3-dioxohydrindene Properties, Molecular Formula, Applications - WorldOfChemicals

2,2-Dihydroxy-1,3-dioxohydrindene Properties


2,2-Dihydroxy-1,3-dioxohydrindene Molecular Structure-Molecule 3D Struture
Molecule 3D Structure Image
2,2-Dihydroxy-1,3-dioxohydrindene Structure-Molecule Struture
Molecule Structure Image



2,2-Dihydroxy-1,3-dioxohydrindene is a chemical used to detect ammonia or primary and secondary amines. When reacting with these free amines, a deep blue or purple color known as Ruhemann's purple is produced. It is most commonly used to detect fingerprints, as the terminal amines of lysine residues in peptides and proteins sloughed off in fingerprints react with ninhydrin. It can also be used to monitor deprotection in solid phase peptide synthesis (Kaiser Test). The chain is linked via its C-terminus to the solid support, with the N-terminus extending off it. When that nitrogen is deprotected, a ninhydrin test yields blue. Amino-acid residues are attached with their N-terminus protected, so if the next residue has been successfully coupled onto the chain, the test gives a colorless or yellow result.

Chemical Properties

Appearance White Solid
Boiling Point 449.3 °C
CAS Number 485-47-2
Density 0.862 g/cm3
EINECS Number 207-618-1
HS Code 291443000
IUPAC Name 2,2-Dihydroxyindane-1,3-dione
InChI 1S/C9H6O4/c10-7-5-3-1-2-4-6(5)8(11)9(7,12)13/h1-4,12-13H
Melting Point 250 °C
Molar Mass 178.14 g/mol
Molecular Formula C9H6O4
RTECS Number NK5425000
Solubility 0.1-0.5 g/100 ml
Synonyms 2,2-Dihydroxyindane-1,3-dione;1H-Indene-1,3(2H)-dione,2,2-dihydroxy-;Ninhydrin;1,3-Indandione,2,2-dihydroxy-;1H-Indene-1,2,3-trione, 2-hydrate;2,2-Dihydroxy-1,3-dioxoindan;2,2-Dihydroxy-1,3-indandione;2,2-Dihydroxy-1H-indene-1,3(2H)-dione;2,3-Dihydro-2,2-dihydroxy-1,3-dioxo-1H-indene;Indane-1,2,3-trione Monohydrate;Triketohydrindene Hydrate;2,2-Dihydroxy-1,3-dioxohydrindene
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