4-Aminopyridine Properties, Molecular Formula, Applications - WorldOfChemicals

4-Aminopyridine Properties

4-Aminopyridine

Sodium 1-lauroyl-L-prolinate-Product_Structure
Molecule 3D Structure Image
Sodium 1-lauroyl-L-prolinate-Molecule 3D Structure
Molecule Structure Image

Description

 

4-Aminopyridine is a pyridne compound. It is as a precursor to the drug pinacidil. It is also used as a bird control agent. It is used primarily as a research tool, in characterizing subtypes of potassium channel, and has also been used to manage some of the symptoms of multiple sclerosis, and is indicated for symptomatic improvement of walking in adults with several variations of the disease. It is prepared by the decarbonylation of pyridine-4-carboxamide using sodium hypochlorite via the Hofmann rearrangement. 4-Aminopyridine is a useful pharmacological tool in studying various potassium conductance in physiology and biophysics. It is a relatively selective blocker of members of Kv1 (Shaker, KCNA) family of voltage-activated K+ channels. 4-Aminopyridine is also used under the trade name Avitrol as 0.5% or 1% in bird control bait. It causes convulsions and, infrequently, death, depending on dosage.

Chemical Properties

Appearance Colourless Solid
Boiling Point 273 °C
CAS Number 504-24-5
Chemical Composition Potassium Carbonate;Pathalic Acid;Pyridine-N-Oxide;4-Nitropyridine
Class 6.1
Density 1.107 g/cm3
EINECS Number 207-987-9
HS Code 29333999
IUPAC Name 4-aminopyridine
InChI 1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
InChIKey NUKYPUAOHBNCPY-UHFFFAOYSA-N
Melting Point 158°C
Molar Mass 94.013 g/mol
Molecular Formula C5H6N2
PG 2
RTECS Number US1750000
Refractive 1.587 n/D
Solubility Soluble
Synonyms 4-AP;P-Aminopyridine;Gamma-Aminoppyridine;Amino-4-Pyridine
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