ABT-737 Properties, Molecular Formula, Applications - WorldOfChemicals

ABT-737 Properties


Molecule Structure Image



ABT-737 is a potent small-molecule inhibitor of antiapoptotic proteins Bcl-2, Bcl-X(L) and Bcl-w with markedly higher affinity than previously reported compounds. ABT-737 induces apoptosis in MM cells, including those resistant to conventional therapy.

Chemical Properties

CAS Number 852808-04-9
IUPAC Name (R)-4-(4-((4'-chloro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-(dimethylamino)-1-(phenylthio)butan-2-yl)amino)-3-nitrophenyl)sulfonyl)benzamide
Molar Mass 813.43 g/mol
Molecular Formula C42H45ClN6O5S2