Acetylcysteine Properties, Molecular Formula, Applications - WorldOfChemicals

Acetylcysteine Properties


Molecule 3D Structure Image
Molecule Structure Image



Acetylcysteine is the acetylated form of L-cysteine.It is a pharmaceutical drug and nutritional supplement used primarily as a mucolytic agent and in the management of paracetamol (acetaminophen) overdose.It is used as a cough medicine because it breaks disulfide bonds in mucus and liquefies it, making it easier to cough up. It is also this action of breaking disulfide bonds that makes it useful in thinning the abnormally thick mucus in Cystic Fibrosis patients.It is very efficiently absorbed and has been shown to protect cells directly and support the immune system. Acetylcysteine is an antioxidant and a free radical-scavenging agent that increases intracellular glutathione at the cellular level.It can act as a precursor for glutathione synthesis as well as a stimulator of the cytosolic enzymes involved in glutathione regeneration.It is used in medical treatment of chronic bronchitis, cancer, and paracetamol intoxication.

Chemical Properties

Appearance White Crystalline Powder
Boiling Point 407.7°C
Brand Name ACC;Acemuc;Acetyst;Acetadote;Asist;Bronkyl;Brunac;Fluimucil;Fluimukan;Flumil;Flutafin;Lysox ;Mucinac;Mucohelp;Mucolysin;Mucomelt-A;MUCOMIX;Mucomyst;NAC AL;Nytex;Parvolex;PharmaNAC;Rheunac;Siran;Solmucaine;Trebon N
CAS Number 616-91-1
ChEBI 28939
Density 1.294 g/cm3
HS Code 29309016
IUPAC Name (R)-2-Acetamido-3-sulfanylpropanoic acid
InChI 1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
Melting Point 106-108 °C(lit.)
Molar Mass 163.19 g/mol
Molecular Formula C5H9NO3S
NFPA 704 H-2, F-1,R-0, C-NA
RTECS Number HA1660000
Solubility 100 mg/ml
Synonyms (S)-Alpha-Amino-2-Naphthalenepropionic Acid;Rarechem Bk Pt 0097;N-Acetyl Cysteine;N-Acetyl-3-Mercaptoalanine;N-Acetyl-L-(+)-Cysteine;N-Acetyl-L-Cysteine;N-Alpha-Acetyl-L-Cysteine;3-(2-Naphthyl)-Alanine;N-Acetyl-L-Cysteine [Cysteine-1-14C]