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Aldosterone Properties

Aldosterone

Molecule Structure Image

Description

 

Aldosterone is a hormone that increases the reabsorption of sodium ions and water and the release (secretion) of potassium ions in the collecting ducts and distal convoluted tubule of the nephron.It is synthesized exclusively in the zona glomerulosa of the adrenal gland.Aldosterone is a yellow steroid hormone (mineralocorticoid family) produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the nephron, the functioning unit of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure.Its activity is reduced in Addison's disease and increased in Conn's syndrome.It was first isolated by Simpson and Tait in 1953.Aldosterone is the primary of several endogenous members of the class of mineralocorticoids in humans.It is involved in regulating aldosterone and is the core regulation.

Chemical Properties

Boiling Point 568.1 °C
CAS Number 52-39-1
ChEBI 27584
Density 1.28 g/cm3
EINECS Number 200-139-9
InChI 1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1
InChIKey PQSUYGKTWSAVDQ-ZVIOFETBSA-N
Melting Point 170-172°C
Molar Mass 360.44 g/mol
Molecular Formula C21H28O5
Synonyms (+)-Aldosterone;Oxocorticosterone;Aldocorten;Aldocortene;Aldocortin;Electrocortin;Elektrocortin; Reichstein X;d-Aldosterone