All-trans retinoic acid. Properties, Molecular Formula, Applications - WorldOfChemicals

All-trans retinoic acid. Properties

All-trans retinoic acid.

Molecule 3D Structure Image
Molecule Structure Image



Tretinoin is most commonly used as a form of acne treatment.[1] It was the first retinoid developed for this type of topical use. Tretinoin is the best studied retinoid in the treatment of photoaging.[2] It is used by some as a hair loss treatment and also a component of many commercial products that are advertised as being able to slow skin aging or remove wrinkles. Topical tretinoin is also used to treat and reduce the appearance of stretch marks by increasing collagen production in the dermis.

Chemical Properties

Appearance Yellow-Orange Powder
Brand Name Aberela, Airol, Renova, Atralin, Retin-A, Avita, Stieva-A
CAS Number 302-79-4
ChEBI 15367
EINECS Number 206-129-0
IUPAC Name retinoic acid
Melting Point 180-181 °C(lit.)
Molar Mass 300.4412 g/mol
Molecular Formula C20H28O2
NFPA 704 H-2, F-1, R-0, C-NA
RTECS Number VH6475000
Solubility insoluble
Synonyms Tretinoin;Tretinoin Vitamin A Acid;Trans-Retinoic Acid;Trans Vitamin A Acid;Vitamin A Acid;Vitamin A Acid, All-Trans;Retinoic Acid;Retinoic Acid, All Trans