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Amodiaquine Properties

Amodiaquine

Molecule Structure Image

Description

 

Amodiaquine is a 4-aminoquinoline compound related to chloroquine, used as an antimalarial and anti-inflammatory agent. It is a histamine N-methyltransferase inhibitor. It has been shown to be more effective than chloroquine in treating CRPF malaria infections and may afford more protection than chloroquine when used as weekly prophylaxis.

Chemical Properties

Appearance Cyrstalline solid
Brand Name Camoquin;Flavoquine
CAS Number 86-42-0
ChEBI 2674
Density 1.258 g/cm3
EINECS Number 201-669-3
IUPAC Name 4-[(7-Chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol
InChI 1S/C20H22ClN3O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19/h5-12,25H,3-4,13H2,1-2H3,(H,22,23)
InChIKey OVCDSSHSILBFBN-UHFFFAOYSA-N
Melting Point 208°C
Molar Mass 355.861 g/mol
Molecular Formula C20H22ClN3O
Synonyms Phenol,4-[(7-chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]-;Amodiaquine;o-Cresol,4-[(7-chloro-4-quinolyl)amino]-a-(diethylamino)-;7-Chloro-4-(3-diethylaminomethyl-4-hydroxyanilino)quinoline;Amodiaquin