Articaine hydrochloride Properties, Molecular Formula, Applications - WorldOfChemicals

Articaine hydrochloride Properties

Articaine hydrochloride

Molecule Structure Image

Description

 

Articaine hydrochloride is the most widely used local anesthetic agent in dentistry. The amide structure of articaine is similar to that of other local anasthetics, but it contains an additional ester group which is quickly hydrolysed by esterases. Articaine has an equal analgesic efficacy as other amide-type local anesthetics, but lower systemic toxicity.

Chemical Properties

Appearance White Crystalline Powder
Boiling Point 440.6 °C
CAS Number 23964-57-0
EINECS Number 245-957-7
IUPAC Name methyl 4-methyl-3-[(N-propylalanyl)amino]thiophene-2-carboxylate hydrochloride
InChI 1S/C13H20N2O3S.ClH/c1-5-6-14-9(3)12(16)15-10-8(2)7-19-11(10)13(17)18-4;/h7,9,14H,5-6H2,1-4H3,(H,15,16);1H
InChIKey GDWDBGSWGNEMGJ-UHFFFAOYSA-N
Molar Mass 320.84 g/mol
Molecular Formula C13H20N2O3S.HCl
Synonyms 2-Thiophenecarboxylic Acid, 4-Methyl-3-[[1-Oxo-2-(Propylamino)Propyl]Amino]-, Methyl Ester, Hydrochloride (1:1);2-Thiophenecarboxylic Acid, 4-Methyl-3-[[1-Oxo-2-(Propylamino)Propyl]Amino]-, Methyl Ester, Monohydrochloride;P4-Méthyl-3-{[2-(Propylamino)Propanoyl]Amino}Thiophène-2-Carboxylate De Méthyle Chlorhydrate;Articaine Hcl;Methyl 4-Methyl-3-[(N-Propylalanyl)Amino]Thiophene-2-Carboxylate Hydrochloride;Methyl 4-Methyl-3-[(N-Propylalanyl)Amino]Thiophene-2-Carboxylate Hydrochloride (1:1);Methyl 4-Methyl-3-{[2-(Propylamino)Propanoyl]Amino}Thiophene-2-Carboxylate Hydrochloride;Methyl-4-Methyl-3-{[2-(Propylamino)Propanoyl]Amino}Thiophen-2-Carboxylathydrochlorid;2-Thiophenecarboxylic Acid, 4-Methyl-3-((1-Oxo-2-(Propylamino)Propyl)Amino)-, Methyl Ester, Monohydrochloride