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Azimilide Properties

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Azimilide

Molecule Structure Image

Description

Azimilide is a class ??? antiarrhythmic drug. The agents from this heterogeneous group have an effect on the repolarization, they prolong the duration of the action potential and the refractory period. Also they slow down the spontaneous discharge frequency of automatic pacemakers by depressing the slope of diastolic depolarization. They shift the threshold towards zero or hyperpolarize the membrane potential. Although each agent has its own properties and will have thus a different function.

Chemical Properties

CAS Number	149908-53-2
ChEBI	308679
Density	1.32 g/cm³
IUPAC Name	1-({(E)-[5-(4-Chlorophenyl)furan-2-yl]methylidene}amino)-3-[4-(4-methylpiperazin-1-yl)butyl]imidazolidine-2,4-dione
InChI	1S/C23H28ClN5O3/c1-26-12-14-27(15-13-26)10-2-3-11-28-22(30)17-29(23(28)31)25-16-20-8-9-21(32-20)18-4-6-19(24)7-5-18/h4-9,16H,2-3,10-15,17H2,1H3/b25-16+
InChIKey	MREBEPTUUMTTIA-PCLIKHOPSA-N
Molar Mass	457.953 g/mol
Molecular Formula	C₂₃H₂₈ClN₅O₃
Synonyms	2,4-Imidazolidinedione,1-[[[5-(4-chlorophenyl)-2-furanyl]methylene]amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-;Azimilide

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