Benfluorex Properties, Molecular Formula, Applications - WorldOfChemicals

Benfluorex Properties

Benfluorex

Molecule Structure Image

Description

 

Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine. Clinical studies have shown it may improve glycemic control and decrease insulin resistance in people with poorly controlled type 2 diabetes. On 18 December 2009 the European Medicines Agency (EMEA) recommended the withdrawal of all medicines containing benfluorex in the European Union, because their risks, particularly the risk of heart valve disease, are greater than their benefits.

Chemical Properties

CAS Number 23602-78-0
Density 1.183 g/cm3
EINECS Number 245-801-8
IUPAC Name (RS)-2-({1-[3-(Trifluoromethyl)phenyl]propan- 2-yl}amino)ethyl benzoate
InChI 1S/C19H20F3NO2/c1-14(12-15-6-5-9-17(13-15)19(20,21)22)23-10-11-25-18(24)16-7-3-2-4-8-16/h2-9,13-14,23H,10-12H2,1H3
InChIKey CJAVTWRYCDNHSM-UHFFFAOYSA-N
Molar Mass 351.363 g/mol
Molecular Formula C19H20F3NO2
Synonyms Ethanol,2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]-, 1-benzoate;Ethanol, 2-[[a-methyl-m-(trifluoromethyl)phenethyl]amino]-,benzoate (ester);1-(m-Trifluoromethylphenyl)-2-([b-benzoyloxyethyl]-amino)propane;N-(2-Benzoyloxyethyl)norfenfluramine;Benfluorex