Bunazosin Properties, Molecular Formula, Applications - WorldOfChemicals

Bunazosin Properties


Molecule Structure Image



Bunazosin is an alpha 1 antagonist. It was initially developed to treat benign prostatic hyperplasia. It has been approved in Japan in a topical form to treat glaucoma. The mechanism of action is a reduction of aqueous outflow through the uveoscleral pathway resulting in lowering the intraocular pressure. It also may act to improve blood flow to the ocular nerve.

Chemical Properties

CAS Number 80755-51-7
Density 1.221 g/cm3
IUPAC Name 1-(4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)-1,4-diazepan-1-yl)butan-1-one
InChI 1S/C19H27N5O3/c1-4-6-17(25)23-7-5-8-24(10-9-23)19-21-14-12-16(27-3)15(26-2)11-13(14)18(20)22-19/h11-12H,4-10H2,1-3H3,(H2,20,21,22)
Molar Mass 373.44 g/mol
Molecular Formula C19H27N5O3
Synonyms 1-Butanone,1-[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)hexahydro-1H-1,4-diazepin-1-yl]-;1H-1,4-Diazepine,1-(4-amino-6,7-dimethoxy-2-quinazolinyl)hexahydro-4-(1-oxobutyl)-;Bunazosin