Bupivacaine Properties, Molecular Formula, Applications - WorldOfChemicals

Bupivacaine Properties


Molecule Structure Image



Bupivacaine is a local anaesthetic drug belonging to the amino amide group. Bupivacaine is indicated for local anesthesia including infiltration, nerve block, epidural, and intrathecal anesthesia. Bupivacaine often is administered by epidural injection before total hip arthroplasty. It also is commonly injected to surgical wound sites to reduce pain for up to 20 hours after the surgery. Bupivacaine binds to the intracellular portion of sodium channels and blocks sodium influx into nerve cells, which prevents depolarization.

Chemical Properties

Brand Name Marcaine;Sensorcaine;Anekain;Bupivan;Carbostesin;Marcain
CAS Number 2180-92-9
IUPAC Name (RS)-1-Butyl-N-(2,6-Dimethylphenyl) Piperidine-2-Carboxamide
InChI 1S/C18H28N2O/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21)/t16-/m0/s1
Molar Mass 288.43 g/mol
Molecular Formula C18H28N2O