Canrenone Properties, Molecular Formula, Applications - WorldOfChemicals

Canrenone Properties

Canrenone

3-Benzoylpyridine-Product_Structure
Molecule Structure Image

Description

 

Canrenone is an aldosterone antagonist with additional antiandrogen properties which is used as a diuretic in Europe. It is a major active metabolite of spironolactone, and is believed to be partially responsible for its effects.

Chemical Properties

Appearance Pale Yellow to Pale Green Solid
Boiling Point 541.1 °C
Brand Name Contaren;Luvion
CAS Number 976-71-6
Density 1.19 g/cm3
EINECS Number 213-554-5
IUPAC Name (8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione
InChI 1S/C22H28O3/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21)12-8-19(24)25-22/h3-4,13,16-18H,5-12H2,1-2H3/t16-,17+,18+,20+,21+,22-/m1/s1
InChIKey UJVLDDZCTMKXJK-WNHSNXHDSA-N
Melting Point 158-160°C
Molar Mass 340.46 g/mol
Molecular Formula C22H28O3
Synonyms (8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione;10,13-dimethylspiro[2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione;Canrenone;17a-Pregna-4,6-diene-21-carboxylicacid, 17-hydroxy-3-oxo-, g-lactone;17-Hydroxy-3-oxo-17a-pregna-4,6-diene-21-carboxylic acid g-lactone;17a-(2-Carboxyethyl)-17b-hydroxyandrosta-4,6-dien-3-one lactone;17b-Hydroxy-3-oxopregna-4,6-diene-21-carboxylicacid;20-Spiroxa-4,6-diene-3,21-dione;3-(17b-Hydroxy-3-oxoandrosta-4,6-dien-17a-yl)propionic acid g-lactone;3'-(3-Oxo-17b-hydroxyandrosta-4,6-dien-17a-yl)-propionic acid lactone;Aldadiene;Phanurane;Contaren;Luvion