Carbamazepine Properties, Molecular Formula, Applications - WorldOfChemicals

Carbamazepine Properties

Carbamazepine

Carbamazepine 3D Structure-Molecule 3D Struture
Molecule 3D Structure Image
Carbamazepine Structure-Molecule Struture
Molecule Structure Image

Description

 

Carbamazepine is an anticonvulsant and mood-stabilizing drug used primarily in the treatment of epilepsy and bipolar disorder, as well as trigeminal neuralgia. It is also used off-label for a variety of indications, including attention-deficit hyperactivity disorder (ADHD), schizophrenia, phantom limb syndrome, complex regional pain syndrome, paroxysmal extreme pain disorder, neuromyotonia, intermittent explosive disorder, borderline personality disorder and post-traumatic stress disorder. Carbamazepine inhibits sustained repetitive firing by blocking use-dependent sodium channels. Carbamazepine also possesses anticholinergic, central antidiuretic, antiarrhythmic, muscle relaxant, antidepressant (possibly through blockade of norepinephrine release), sedative, and neuromuscular-blocking properties.

Chemical Properties

Appearance White Solid
Boiling Point 410.984 °C
Brand Name Atretol;Biston;Calepsin;Carbamazepen;Carbatrol;Carbazepine;Carbelan;Epitol;Equetro;Finlepsin;Karbamazepin;Lexin;Neurotol;Novo-Carbamaz;Nu-Carbamazepine;Sirtal;Stazepin;Stazepine;Taro-Carbamazepine;Taro-Carbamazepine Cr;Tegretal;Tegretol;Tegretol Chewtabs;Tegretol Cr;Tegretol-Xr;Telesmin;Teril;Timonil
CAS Number 298-46-4
ChEBI 3387
Density 1.266 g/cm3
EINECS Number 206-062-7
InChI 1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)
InChIKey FFGPTBGBLSHEPO-UHFFFAOYSA-N
Melting Point 189-192 °C
Molar Mass 236.27 g/mol
Molecular Formula C15H12N2O
RTECS Number HN8225000
Solubility Insoluble
Synonyms CBZ