Carmustine Properties, Molecular Formula, Applications - WorldOfChemicals

Carmustine Properties

Carmustine

Molecule Structure Image

Description

 

Carmustine is a cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms.Carmustine causes cross-links in DNA and RNA, leading to the inhibition of DNA synthesis, RNA production and RNA translation (protein synthesis). Carmustine also binds to and modifies (carbamoylates) glutathione reductase. This leads to cell death.Side effects include leukopenia, thrombocytopenia, nausea.

Chemical Properties

Appearance Light Yellow Powder
Brand Name Becenun;BiCNU;Carmubris(Germany);Gliadel(Australia);(France);(Spain);(United Kingdom);(Usa (Va) Fss Prices);Gliadel Wafer;Nitrumon(Belgium)
CAS Number 154-93-8
Density 1.46 g/cm3
InChI 1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)
InChIKey DLGOEMSEDOSKAD-UHFFFAOYSA-N
Melting Point 31°C
Molar Mass 214.050 g/mol
Molecular Formula C5H9Cl2N3O2
RTECS Number YS2625000
Solubility 0.1 g/100 ml
Synonyms BCNU;Bischlorethylnitrosoureap;Carmustin
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