Catechol-O-methyl transferase Properties, Molecular Formula, Applications - WorldOfChemicals

Catechol-O-methyl transferase Properties

Catechol-O-methyl transferase

Molecule 3D Structure Image

Description

 

Catechol-O-methyltransferase (COMT; EC 2.1.1.6) is one of several enzymes that degrade catecholamines such as dopamine, epinephrine, and norepinephrine. In humans, catechol-O-methyltransferase protein is encoded by the COMT gene. As the regulation of catecholamines is impaired in a number of medical conditions, several pharmaceutical drugs target COMT to alter its activity and therefore the availability of catecholamines.

Chemical Properties