Clopenthixol Properties, Molecular Formula, Applications - WorldOfChemicals

Clopenthixol Properties

Clopenthixol

Molecule Structure Image

Description

 

Clopenthixol is a typical antipsychotic drug of the thioxanthene class. It was introduced by Lundbeck in 1961. It is a racemic mixture of cis and trans isomers. Zuclopenthixol, the pure cis isomer, was later introduced by Lundbeck in 1962, and has been much more widely used. Both drugs are equally effective as antipsychotics and have similar adverse effect profiles, but clopenthixol is half as active on a milligram-to-milligram basis and appears to produce more sedation in comparison.

Chemical Properties

CAS Number 982-24-1
Density 1.289g/cm3
EINECS Number 213-566-0
IUPAC Name cis,trans-2-[4-[3-(2-Chlorothioxanthen-9-ylidene) propyl]piperazin-1-yl]ethanol
InChI 1S/C22H25ClN2OS/c23-17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)27-22)5-3-9-24-10-12-25(13-11-24)14-15-26/h1-2,4-8,16,26H,3,9-15H2
InChIKey WFPIAZLQTJBIFN-UHFFFAOYSA-N
Molar Mass 400.965 g/mol
Molecular Formula C22H25ClN2OS
Synonyms 1-Piperazineethanol,4-[3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]-;Clopenthixol;Sordinol;Clopentixol;2-(4-[3-(2-Chloro-9-thioxanthenylidene)propyl]-1-piperazinyl)ethanol;4-[3-(2-Chlorothioxanthen-9-ylidene)propyl]-1-piperazineethanol;Chlorpenthixol