Donepezil Hydrochloride Properties, Molecular Formula, Applications - WorldOfChemicals

Donepezil Hydrochloride Properties

Donepezil Hydrochloride

Molecule Structure Image

Description

 

Donepezil hydrochloride is a centrally acting reversible acetyl cholinesterase inhibitor. Its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.

Chemical Properties

Appearance White to Off-white Crystalline Solid
CAS Number 120011-70-3
ChEBI 4696
IUPAC Name 2-[(1-Benzyl-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone hydrochloride (1:1)
InChI 1/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3
InChIKey XWAIAVWHZJNZQQ-FTBWJZELCQ
Melting Point 220-222 °C
Molar Mass 415.95 g/mol
Molecular Formula C24H30ClNO3
Synonyms 1H-Inden-1-one,2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-,hydrochloride;Donepezil Hydrochloride;2-[(1-Benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride;1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hcl