Floxacillin Properties, Molecular Formula, Applications - WorldOfChemicals

Floxacillin Properties

Floxacillin

Molecule 3D Structure Image
Molecule Structure Image

Description

 

Floxacillin is a narrow-spectrum beta-lactam antibiotic of the penicillin class. It is used to treat infections caused by susceptible Gram-positive bacteria. Unlike other penicillins, flucloxacillin has activity against beta-lactamase-producing organisms such as Staphylococcus aureus as it is beta-lactamase stable. However, it is ineffective against MRSA. It is very similar to dicloxacillin and these two agents are considered interchangeable.

Chemical Properties

Appearance White to off white free flowing crystalline powder
Brand Name Floxapen;Flopen;Luf;Flubex
CAS Number 5250-39-5
ChEBI 5098
Density 1.59 g/cm3
EINECS Number 226-051-0
IUPAC Name (2S,5R,6R)-6-({[3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
InChI 1S/C19H17ClFN3O5S/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28)/t13-,14+,17-/m1/s1
InChIKey UIOFUWFRIANQPC-JKIFEVAISA-N
Molar Mass 453.87 g/mol
Molecular Formula C19H17ClFN3O5S
Synonyms 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[[[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-,(2S,5R,6R)-;6-[3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolecarboxamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid;Flucloxacillin;Floxacillin