Gabapentin Properties, Molecular Formula, Applications - WorldOfChemicals

Gabapentin Properties

Gabapentin

Molecule 3D Structure Image
Molecule Structure Image

Description

 

Gabapentin is a GABA analogue.It may also be used for treating nerve pain associated with herpes zoster (shingles) infection (postherpetic neuralgia). Gabapentin is an anticonvulsant used to treat seizures associated with epilepsy. It may also be used to treat pain due to abnormal nerve stimulation (neuropathic pain) and nerve pain associated with herpes zoster infection.Gabapentin interacts with cortical neurons at auxillary subunits of voltage-sensitive calcium channels.It increases the synaptic concentration of GABA, enhances GABA responses at non-synaptic sites in neuronal tissues, and reduces the release of mono-amine neurotransmitters.

Chemical Properties

Appearance White Crystalline Solid
Boiling Point 314.4°C
Brand Name Fanatrex;Gabarone;Gralise;Neurontin;Nupentin
CAS Number 60142-96-3
Density 1.058 g/cm3
EINECS Number 262-076-3
IUPAC Name [1-(Aminomethyl)cyclohexyl]acetic acid
InChI 1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)
InChIKey UGJMXCAKCUNAIE-UHFFFAOYSA-N
Melting Point 162-166°C
Molar Mass 171.237 g/mol
Molecular Formula C9H17NO2
RTECS Number GU6496000
Solubility Soluble
Synonyms 1-(Aminomethyl)cyclohexaneacetic Acid;Cyclohexaneacetic acid, 1-(aminomethyl)-;Gabapentino;Neurontin;Go 3450;CI 945;Gabapentine;2-[1-(Aminomethyl)cyclohexyl]acetic Acid;GOE 2450;2-[1(Azaniumylmethyl)cyclohexyl]acetate;Gabapentin;Gabapentino;Gabapentine;Garbapentin;Gabapetine