Gatifloxacin Properties, Molecular Formula, Applications - WorldOfChemicals

Gatifloxacin Properties

Gatifloxacin

Molecule Structure Image

Description

 

Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family. Inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.Well absorbed from the gastrointestinal tract after oral administration with absolute bioavailability of gatifloxacin is 96%.

Chemical Properties

Appearance White to light yellow powder
Boiling Point 607.8 °C
Brand Name Tequin
Zymar
Zymaxid
CAS Number 112811-59-3
Density 1.386 g/cm3
IUPAC Name 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
InChI 1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26)
InChIKey XUBOMFCQGDBHNK-UHFFFAOYSA-N
Melting Point 182-185 °C
Molar Mass 375.39 g/mol
Molecular Formula C19H22FN3O4
Solubility 60 mg/ml
Synonyms Gatifloxacin;1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid;1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid;1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-4-ium-1-yl)-4-oxoquinoline-3-carboxylate