Gemcitabine Hydrochloride Properties, Molecular Formula, Applications - WorldOfChemicals

Gemcitabine Hydrochloride Properties

Gemcitabine Hydrochloride

Molecule Structure Image



Gemcitabine hydrochloride is an analogue of cytarabine that is metabolised intracellularly to active diphosphate and triphosphate nucleosides, which inhibit DNA synthesis and induce apoptosis. It is primarily active against cells in S phase. It is given in the management of solid tumours including those of the bladder, breast, lung, ovary, and pancreas.

Chemical Properties

Appearance White to Off-white Crystalline Powder
Boiling Point 482.7 °C
Brand Name Gemzar
CAS Number 122111-03-9
IUPAC Name 2'-Deoxy-2',2'-difluorocytidine hydrochloride
InChI 1S/C9H11F2N3O4.ClH/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17;/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17);1H/t4-,6-,7-;/m1./s1
Melting Point >250°C
Molar Mass 299.66 g/mol
Molecular Formula C9H12ClF2N3O4
Solubility Soluble
Synonyms Gemcitabine HCl;2',2'-Difluorodeoxycytidine Monohydrochloride;2'-Deoxy-2',2'-difluorocytidine Monohydrochloride;Gemcitabine Hydrochloride uses cookies to ensure that we give you the best experience on our website. By using this site, you agree to our Privacy Policy and our Terms of Use. X