Hesperidin Properties, Molecular Formula, Applications - WorldOfChemicals

Hesperidin Properties


Molecule Structure Image



Hesperidin is a flavanone glycoside found abundantly in citrus fruits. Its name is derived from the Hesperides nymphs of Greek mythology. It is believed to play a role in plant defense. It acts as an antioxidant according to in vitro studies. In human nutrition, it contributes to the integrity of the blood vessels. Various preliminary studies reveal novel pharmaceutical properties. It reduces cholesterol and blood pressure in rats. It has anti-inflammatory effects. It is also a potential sedative, possibly acting through opioid or adenosine receptors. Hesperidin also showed the ability to penetrate the blood-brain barrier in an in vitro model.

Chemical Properties

Appearance Light brown powder
CAS Number 520-26-3
Density 1.65 g/cm3
EINECS Number 208-288-1
IUPAC Name (2S)-5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochromen-4-one
InChI 1S/C28H34O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-7,10,17,19,21-30,32-37H,8-9H2,1-2H3/t10-,17-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1
Melting Point 250-255 °C
Molar Mass 610.56 g/mol
Molecular Formula C28H34O15
RTECS Number MK6650000
Synonyms Hesperidin;Hesperidoside