Heterocodeine Properties, Molecular Formula, Applications - WorldOfChemicals

Heterocodeine Properties

Heterocodeine

Molecule Structure Image

Description

 

Heterocodeine is an opiate derivative, the 6-methyl ether of morphine, and a structural isomer of codeine. It was first synthesised in 1932, and can be made from morphine by selective methylation. It is 6 times more potent than morphine due to having a substitution at the 6-hydroxy position, in a similar manner to 6-acetylmorphine The drug methyldihydromorphine is a derivative of heterocodeine.

Chemical Properties

CAS Number 639-47-4
Density 1.34g/cm3
EINECS Number 211-356-3
IUPAC Name (5α,6α)-6-Methoxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3-ol
InChI 1S/C18H21NO3/c1-19-8-7-18-11-4-6-14(21-2)17(18)22-16-13(20)5-3-10(15(16)18)9-12(11)19/h3-6,11-12,14,17,20H,7-9H2,1-2H3/t11-,12+,14-,17-,18-/m0/s1
InChIKey FNAHUZTWOVOCTL-XSSYPUMDSA-N
Molar Mass 299.364 g/mol
Molecular Formula C18H21NO3
Synonyms Heterocodeine;6-Methylmorphine;Morphinan-3-ol,7,8-didehydro-4,5-epoxy-6-methoxy-17-methyl-, (5a,6a)-;Morphine-6-methyl ether