Kongensin A Properties, Molecular Formula, Applications - WorldOfChemicals

Kongensin A Properties

Kongensin A

Molecule Structure Image

Description

 

Kongensin A is a non-canonical HSP90 inhibitor that covalently binds to HSP90, thereby blocking RIP3-dependent necroptosis.

Chemical Properties

CAS Number 885315-96-8
IUPAC Name (2R,4R,8R,9S,13R)-2-Hydroxy-5,5,9-trimethyl-14-methylene-10,15-dioxotricyclo[11.2.1.0~4,9~]hexadec-1(16)-en-8-yl acetate
InChI 1S/C22H30O5/c1-12-14-6-7-18(25)22(5)17(11-16(24)15(10-14)20(12)26)21(3,4)9-8-19(22)27-13(2)23/h10,14,16-17,19,24H,1,6-9,11H2,2-5H3/t14-,16-,17-,19-,22-/m1/s1
InChIKey NUUWPMNNBHROPI-ASAQZKIWSA-N
Molar Mass 374.48 g/mol
Molecular Formula C22H30O5
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