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Kynurenic Acid Properties

Kynurenic Acid

Molecule Structure Image

Description

 

Kynurenic acid is a product of the normal metabolism of amino acid L-tryptophan. It has been shown that kynurenic acid possesses neuroactive activity. It acts as an antiexcitotoxic and anticonvulsant, most likely through acting as an antagonist at excitatory amino acid receptors. Because of this activity, it may influence important neurophysiologic and neuropathologic processes. As a result, kynurenic acid has been considered for use in therapy in certain neurobiological disorders. Conversely, increased levels of kynurenic acid have also been linked to certain pathological conditions.

Chemical Properties

Appearance Off-White to Tan Powder
CAS Number 492-27-3
EINECS Number 207-751-5
IUPAC Name 4-Oxo-1H-Quinoline-2-Carboxylic Acid
InChI 1S/C10H7NO3/c12-9-5-8(10(13)14)11-7-4-2-1-3-6(7)9/h1-5H,(H,11,12)(H,13,14)
InChIKey HCZHHEIFKROPDY-UHFFFAOYSA-N
Melting Point 282.5°C
Molar Mass 189.168 g/mol
Molecular Formula C10H7NO3
RTECS Number UZ9300000
Solubility Soluble
Synonyms Kinurenic acid;Kynuronic acid;Quinurenic acid;Transtorine;4-Hydroxquinoline-2-carboxylic acid;4-Hydroxyquinaldic acid;4-Hydroxy-2-quinolincarboxylicacid;2-Quinolinecarboxylic acid, 4-hydroxy-