Metirosine Properties, Molecular Formula, Applications - WorldOfChemicals

Metirosine Properties


Molecule Structure Image



Metirosine is an antihypertensive drug. It inhibits the enzyme tyrosine hydroxylase and, therefore, catecholamine synthesis, which, as a consequence, depletes the levels of the catecholamines dopamine, adrenaline and noradrenaline in the body. It has been used in the treatment of pheochromocytoma. It is contra-indicated for the treatment of essential hypertension. However it is now rarely used in medicine, and its main use is in scientific research, to investigate the effects of catecholamine depletion on behaviour.

Chemical Properties

Appearance White solid
CAS Number 672-87-7
EINECS Number 211-599-5
IUPAC Name (2S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid
InChI 1S/C10H13NO3/c1-10(11,9(13)14)6-7-2-4-8(12)5-3-7/h2-5,12H,6,11H2,1H3,(H,13,14)/t10-/m0/s1
Melting Point 320-340°C
Molar Mass 195.215 g/mol
Molecular Formula C10H13NO3
Synonyms Metirosine;α-Methyltyrosine;Metyrosine;AMPT;L-Tyrosine, a-methyl-;Tyrosine,a-methyl-, L- uses cookies to ensure that we give you the best experience on our website. By using this site, you agree to our Privacy Policy and our Terms of Use. X