Moxifloxacin Properties, Molecular Formula, Applications - WorldOfChemicals

Moxifloxacin Properties

Moxifloxacin

Molecule 3D Structure Image
Molecule Structure Image

Description

 

Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.The bactericidal action of moxifloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division. Symptoms of overdose include CNS and gastrointestinal effects such as decreased activity, somnolence, tremor, convulsions, vomiting, and diarrhea.

Chemical Properties

Boiling Point 636.4°C
Brand Name Avelox;Avalox;Avelon;Vigamox
CAS Number 354812-41-2
IUPAC Name 1-Cyclopropyl-7-[(1S,6S)-2,8-Diazabicyclo
[4.3.0]non-8-yl]-6-Fluoro-8-Methoxy-4-oxo- Quinoline-3-Carboxylic Acid
InChI 1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1
InChIKey FABPRXSRWADJSP-MEDUHNTESA-N
Melting Point 238-242°C
Molar Mass 401.431 g/mol
Molecular Formula C21H24FN3O4
Synonyms BAY 12-8039;Moxifloxacin
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