neostigmine Properties, Molecular Formula, Applications - WorldOfChemicals

neostigmine Properties


Molecule 3D Structure Image
Molecule Structure Image



Neostigmine is a parasympathomimetic that acts as a reversible acetylcholinesterase inhibitor.Neostigmine is made by first reacting 3-dimethylaminophenol with N-dimethylcarbamoyl chloride, which forms a dimethylcarbamate. It is used to improve muscle tone in people with myasthenia gravis and routinely in anesthesia to reverse the effects of non-depolarizing muscle relaxants such as rocuronium and vecuronium at the end of an operation, usually in a dose of 25 to 50 ?g per kilogram.It can also be used for urinary retention resulting from general anesthesia and to treat curariform drug toxicity.

Chemical Properties

CAS Number 59-99-4
ChEBI 7514
IUPAC Name 3-{[(dimethylamino)carbonyl]oxy}-N,N,N-trimethylbenzenaminium
InChI InChI=1/C12H19N2O2/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5/h6-9H,1-5H3/q+1
Molar Mass 223.294 g/mol
Molecular Formula C12H19N2O2