Norepinephrine Properties, Molecular Formula, Applications - WorldOfChemicals

Norepinephrine Properties


Molecule 3D Structure Image
Molecule Structure Image



Norepinephrine a catecholamine, which is the principal neurotransmitter of postganglionic adrenergic neurons, having predominant α-adrenergic activity. It is a hormone secreted by certain nerve endings of the sympathetic nervous system, and by the medulla (center) of the adrenal glands. Its primary function is to help maintain a constant blood pressure by stimulating certain blood vessels to constrict when the blood pressure falls below normal. Norepinephrine is synthesized from dopamine by dopamine β-hydroxylase. It is released from the adrenal medulla into the blood as a hormone, and is also a neurotransmitter in the central nervous system and sympathetic nervous system. It affects parts of the brain, such as the amygdala, where attention and responses are controlled, triggering the release of glucose from energy stores, and increasing blood flow to skeletal muscle. It increases the brain's oxygen supply. Norepinephrine is synthesized from tyrosine as a precursor, and packed into synaptic vesicles. It stimulates the production of adrenaline, which makes our heart race, and the palms sweat, and increases the experience of joy and reduces appetite. In humans Norepinephrine prompts first attraction, first "sparks" in the air followed by falling in love.

Chemical Properties

Appearance Off-White to Tan Solid
Boiling Point 442.6 °C
CAS Number 51-41-2
ChEBI 18357
Density 1.397 g/cm3
EINECS Number 205-750-4
IUPAC Name 4-[(1R)-2-Amino-1-hydroxyethyl]benzene-1,2-diol
InChI 1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1
Melting Point 220-230 °C
Molar Mass 169.18 g/mol
Molecular Formula C8H11NO3
RTECS Number DN5950000
Synonyms Noradrenaline; (R)-(-)-Norepinephrine; l-1-(3,4-Dihydroxyphenyl)-2-Aminoethanol; (-)-Norepinephrine; (R)-noradrenaline; (R)-Norepinephrine